Chemical Compound Review:
Sandimmun 30-ethyl-33-[(Z,1S,2R)-1- hydroxy-2-methyl...
Synonyms:
Consupren, Sandimmune, Ciclosporin, Cyclosporin, cyclosporine, ...
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- HIV results in the frame. Cyclosporin A. Weber, J., Galpin, S. Nature (1995)
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- Cellular functions of immunophilins. Marks, A.R. Physiol. Rev. (1996)
- Regression of established tumors expressing P-glycoprotein by combinations of adriamycin, cyclosporin derivatives, and MRK-16 antibodies. Watanabe, T., Naito, M., Kokubu, N., Tsuruo, T. J. Natl. Cancer Inst. (1997)
- Enhanced development of atherosclerosis in cholesterol-fed rabbits by suppression of cell-mediated immunity. Roselaar, S.E., Schonfeld, G., Daugherty, A. J. Clin. Invest. (1995)
- Effects of cyclosporin A and alpha-difluoromethylornithine on the growth of hamster pancreatic cancer in vitro. Saydjari, R., Townsend, C.M., Barranco, S.C., James, E., Thompson, J.C. J. Natl. Cancer Inst. (1986)
- Cyclosporin prevents diabetes in BB Wistar rats. Laupacis, A., Stiller, C.R., Gardell, C., Keown, P., Dupre, J., Wallace, A.C., Thibert, P. Lancet (1983)
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- The latch region of calcineurin B is involved in both immunosuppressant-immunophilin complex docking and phosphatase activation. Milan, D., Griffith, J., Su, M., Price, E.R., McKeon, F. Cell (1994)
- A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase. Harding, M.W., Galat, A., Uehling, D.E., Schreiber, S.L. Nature (1989)
- Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes. Shi, Y.F., Sahai, B.M., Green, D.R. Nature (1989)
- High brain densities of the immunophilin FKBP colocalized with calcineurin. Steiner, J.P., Dawson, T.M., Fotuhi, M., Glatt, C.E., Snowman, A.M., Cohen, N., Snyder, S.H. Nature (1992)
- Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy. Kallen, J., Spitzfaden, C., Zurini, M.G., Wider, G., Widmer, H., Wüthrich, K., Walkinshaw, M.D. Nature (1991)
- Sensitivity of human bone marrow cells to cyclosporin A. Francis, G.E., Berney, J.J. Nature (1980)
- Cyclosporin A inhibits growth of autocrine tumour cell lines by destabilizing interleukin-3 mRNA. Nair, A.P., Hahn, S., Banholzer, R., Hirsch, H.H., Moroni, C. Nature (1994)
- Cyclosporin A promotes spontaneous outgrowth in vitro of Epstein-Barr virus-induced B-cell lines. Bird, A.G., McLachlan, S.M., Britton, S. Nature (1981)
- Lymphokine dependence of in vivo expression of MHC class II antigens by endothelium. Groenewegen, G., Buurman, W.A., van der Linden, C.J. Nature (1985)
- IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1. Musarò, A., McCullagh, K.J., Naya, F.J., Olson, E.N., Rosenthal, N. Nature (1999)
- Liver transplantation with use of cyclosporin a and prednisone. Starzl, T.E., Klintmalm, G.B., Porter, K.A., Iwatsuki, S., Schröter, G.P. N. Engl. J. Med. (1981)
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- Prostaglandin E2 and other cyclic AMP elevating agents inhibit interleukin 2 gene transcription by counteracting calcineurin-dependent pathways. Paliogianni, F., Kincaid, R.L., Boumpas, D.T. J. Exp. Med. (1993)
- In vivo induction of interleukin 10 by anti-CD3 monoclonal antibody or bacterial lipopolysaccharide: differential modulation by cyclosporin A. Durez, P., Abramowicz, D., Gérard, C., Van Mechelen, M., Amraoui, Z., Dubois, C., Leo, O., Velu, T., Goldman, M. J. Exp. Med. (1993)
- NFAT and Osterix cooperatively regulate bone formation. Koga, T., Matsui, Y., Asagiri, M., Kodama, T., de Crombrugghe, B., Nakashima, K., Takayanagi, H. Nat. Med. (2005)
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- Interleukin 2 induces the expression of CD45RO and the memory phenotype by CD45RA+ peripheral blood lymphocytes. Roth, M.D. J. Exp. Med. (1994)
- Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: roles of the nuclear factor of activated T cells and cyclooxygenase 2. Hernández, G.L., Volpert, O.V., Iñiguez, M.A., Lorenzo, E., Martínez-Martínez, S., Grau, R., Fresno, M., Redondo, J.M. J. Exp. Med. (2001)
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- Cyclosporin immunosuppression as the possible cause of AIDS. Sell, K.W., Folks, T., Kwon-Chung, K.J., Coligan, J., Maloy, W.L. N. Engl. J. Med. (1983)
- Heart-lung transplantation: successful therapy for patients with pulmonary vascular disease. Reitz, B.A., Wallwork, J.L., Hunt, S.A., Pennock, J.L., Billingham, M.E., Oyer, P.E., Stinson, E.B., Shumway, N.E. N. Engl. J. Med. (1982)
- A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin. Siekierka, J.J., Hung, S.H., Poe, M., Lin, C.S., Sigal, N.H. Nature (1989)
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