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MeSH Review

Time Perception

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Psychiatry related information on Time Perception


High impact information on Time Perception

  • When frequency perception deficits were controlled, only patients with RHD showed time perception deficits [4].
  • Subjects were tested on the following four tasks: the Stop task, which measures the ability to inhibit a prepotent motor response; a Go/no-go task; a Delay discounting task, which measures the value of delayed or uncertain reinforcers; and a time estimation task, which measures alterations in time perception through a time reproduction procedure [5].
  • In this study, our goal was to characterize time perception and reproduction abilities in individuals with VCFS [6].
  • This suggests that time perception is more likely to be altered by diphenhydramine than is performance on tasks requiring short periods of rapid cognitive processing [7].
  • Compared to ethanol and placebo, marijuana induced a significant under-production of time intervals, suggesting an acceleration of the internal rate of time perception [8].

Chemical compound and disease context of Time Perception

  • Specifically, this research shows that a dopamine antagonist, pimozide, changes response rates through the direct action of the drug but changes time perception through the CRs elicited by drug administration [9].
  • Although there is some evidence from animal and human studies suggesting that the internal timing mechanism underlying time perception is modulated by the effective level of brain dopamine, the findings are not conclusive [10].
  • In the present study, we examined whether cholinergic drugs such as arecoline and physostigmine attenuated an impairment of time perception presented by daily scheduled feeding in aged rats [11].
  • In the present experiment, we examined the attenuating effect of bifemelane hydrochloride (BF), 4-(o-benzyl phenoxy)-N-methylbutylamine hydrochloride, on the impairment of time perception caused by daily scheduled feeding using aged and MK-801-treated rats [12].
  • In the present study, we examined attenuating effect of serotonin (5-HT) receptor antagonists on the impairment of the time perception presented by daily scheduled feeding in old rats [13].

Gene context of Time Perception

  • Results extended findings on time perception in ADHD children to adults and ruled out comorbidity as the basis of the errors [14].
  • To assess cannabinoid effects on time perception, this study examined whether systemically administered cannabinoid receptor agonists and a cannabinoid receptor antagonist influenced rats' performance of a time interval estimation task based on a fixed-interval schedule (a "peak procedure") [15].


  1. Association between cognitive performance and striatal dopamine binding is higher in timing and motor tasks in patients with schizophrenia. Yang, Y.K., Yeh, T.L., Chiu, N.T., Lee, I.H., Chen, P.S., Lee, L.C., Jeffries, K.J. Psychiatry research. (2004) [Pubmed]
  2. Multiple behavioral effects of diazepam in rhesus monkeys. Schulze, G.E., Slikker, W., Paule, M.G. Pharmacol. Biochem. Behav. (1989) [Pubmed]
  3. Time perception deficits in attention-deficit/ hyperactivity disorder and comorbid reading difficulties in child and adolescent samples. Toplak, M.E., Rucklidge, J.J., Hetherington, R., John, S.C., Tannock, R. Journal of child psychology and psychiatry, and allied disciplines. (2003) [Pubmed]
  4. Cortical networks underlying mechanisms of time perception. Harrington, D.L., Haaland, K.Y., Knight, R.T. J. Neurosci. (1998) [Pubmed]
  5. Effects of THC on behavioral measures of impulsivity in humans. McDonald, J., Schleifer, L., Richards, J.B., de Wit, H. Neuropsychopharmacology (2003) [Pubmed]
  6. Temporal perception in velo-cardio-facial syndrome. Debbané, M., Glaser, B., Gex-Fabry, M., Eliez, S. Neuropsychologia. (2005) [Pubmed]
  7. Methamphetamine and diphenhydramine effects on the rate of cognitive processing. Mohs, R.C., Tinklenberg, J.R., Roth, W.T., Kopell, B.S. Psychopharmacology (Berl.) (1978) [Pubmed]
  8. Marijuana and ethanol: differential effects on time perception, heart rate, and subjective response. Tinklenberg, J.R., Roth, W.T., Kopell, B.S. Psychopharmacology (Berl.) (1976) [Pubmed]
  9. Conditioned and unconditioned behavioral-cognitive effects of a dopamine antagonist in rats. Ohyama, T., Horvitz, J.C., Drew, M.R., Gibbon, J., Malapani, C., Balsam, P.D. Behav. Neurosci. (2000) [Pubmed]
  10. On dopaminergic modulation of temporal information processing. Rammsayer, T.H. Biological psychology. (1993) [Pubmed]
  11. Attenuating effect of arecoline and physostigmine on an impairment of mealtime-associated activity rhythm in old rats. Ono, M., Minamoto, Y., Shibata, S., Watanabe, S. Physiol. Behav. (1995) [Pubmed]
  12. Attenuating effect of bifemelane on an impairment of mealtime-associated activity rhythm in aged and MK-801-treated rats. Shibata, S., Ono, M., Minamoto, Y., Watanabe, S. Pharmacol. Biochem. Behav. (1995) [Pubmed]
  13. Attenuating effect of serotonin receptor antagonists on impairment of mealtime-associated activity rhythm in old rats. Shibata, S., Ono, M., Minamoto, Y., Watanabe, S. Pharmacol. Biochem. Behav. (1995) [Pubmed]
  14. Time perception and reproduction in young adults with attention deficit hyperactivity disorder. Barkley, R.A., Murphy, K.R., Bush, T. Neuropsychology. (2001) [Pubmed]
  15. Cannabinoid modulation of time estimation in the rat. Han, C.J., Robinson, J.K. Behav. Neurosci. (2001) [Pubmed]
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