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MeSH Review:

Type A Personality

Perini, C. et al., Gan, S.H. et al., Pearson, T.A., Burchfiel, C.M. et al., Kabuto, M. et al., et al.

von Bothmer, Fridlund,

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Disease relevance of Type A Personality

Hispanics had lower serum uric acid levels and greater central obesity than Anglos; they were less likely to have a Type A personality, less physically active at work, and more likely to be a current smoker than Anglos [1].

Psychiatry related information on Type A Personality

Risk factors that require this modification of human behavior include: low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, cigarette smoking, obesity, hypertension, physical activity and, although controversial, coronary prone personality [2].

High impact information on Type A Personality

If decreases in HDL are not in the same causal pathway, then the apparent association between type A personality and risk of MI is due to confounding, principally by HDL [3].
Although debrisoquine hydroxylase (CYP2D6) capacity has been associated with personality, no study has specifically investigated its association with personality Type A and B. Therefore the aim of this research was to study the impact of CYP2D6 on Type A and B personality [4].
A factor analysis identified seven factors related to personality traits; the three most important were hardiness, positive affect/optimism and Type A personality [5].
The association between the total theta power change and "calm" score was found to be insignificant if the type-A personality variable was added to their regression model [6].
Type A personality may strike at the heart of CAD [7].

Chemical compound and disease context of Type A Personality

Trait Anxiety and Type A personality were measured pre-operatively, and plasma cortisol, adrenaline and noradrenaline were measured pre-, per- and post-operatively [8].

Gene context of Type A Personality

This suggests the possibility of a 'hypertensive coronary-prone personality'. Because of their excellent antihypertensive response to chronic beta-blocker therapy, it is conceivable that high renin patients benefit most from the cardioprotective potential of beta-blocker-based antihypertensive therapy [9].

References

Cardiovascular risk factors and impaired glucose tolerance: the San Luis Valley Diabetes Study. Burchfiel, C.M., Hamman, R.F., Marshall, J.A., Baxter, J., Kahn, L.B., Amirani, J.J. Am. J. Epidemiol. (1990) [Pubmed]
Multiple risk factors for coronary artery disease: behavioral factors in preventive cardiology. Pearson, T.A. Am. J. Cardiol. (1987) [Pubmed]
Psychosocial risk factors and nonfatal myocardial infarction. O'Connor, N.J., Manson, J.E., O'Connor, G.T., Buring, J.E. Circulation (1995) [Pubmed]
Relationship between Type A and B personality and debrisoquine hydroxylation capacity. Gan, S.H., Ismail, R., Wan Adnan, W.A., Zulmi, W., Kumaraswamy, N., Larmie, E.T. British journal of clinical pharmacology. (2004) [Pubmed]
Self-rated health among university students in relation to sense of coherence and other personality traits. von Bothmer, M.I., Fridlund, B. Scandinavian journal of caring sciences. (2003) [Pubmed]
EEG power spectrum changes due to listening to pleasant music and their relation to relaxation effects. Kabuto, M., Kageyama, T., Nitta, H. Nippon eiseigaku zasshi. Japanese journal of hygiene. (1993) [Pubmed]
Type A personality may strike at the heart of CAD. Allen, T.W. The Journal of the American Osteopathic Association. (1992) [Pubmed]
Anxiety, type A personality and endocrine responses to surgery. Salmon, P., Pearce, S., Smith, C.C., Manyande, A., Heys, A., Peters, N., Rashid, J. The British journal of clinical psychology / the British Psychological Society. (1989) [Pubmed]
Personality, coronary-prone behaviour and adrenergic factors in essential hypertension: possible implications for cardiac prevention. Perini, C., Müller, F., Bühler, F.R. Activitas nervosa superior. (1982) [Pubmed]

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