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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Vascular Neoplasms

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Disease relevance of Vascular Neoplasms


High impact information on Vascular Neoplasms

  • HCC is a highly vascular neoplasm usually arising in a cirrhotic liver [3].
  • We therefore examined a series of vascular neoplasms of both endothelial and pericyte derivation using polymerase chain reaction to detect a 233-hp segment of the viral DNA [4].
  • In order to verify the expression of estrogen receptors in vascular neoplasms as well as to clarify the inconsistency between radioligand and early immunohistochemical studies, we examined a series of 53 benign and malignant vascular neoplasms for ER beta expression [5].
  • The discrepancy between radioligand studies and previous immunohistochemical studies is attributable to the use of antibodies raised against ER alpha, which is not expressed in vascular lesions, and not ER beta, which is broadly expressed in both benign and malignant vascular neoplasms [5].
  • Utility of the immunohistochemical detection of FLI-1 expression in round cell and vascular neoplasm using a monoclonal antibody [2].

Chemical compound and disease context of Vascular Neoplasms

  • We performed immunohistochemical staining of conventional sections from formalin-fixed, paraffin-embedded tissue from 59 benign and malignant vascular neoplasms using a polyclonal rabbit antiserum against FKBP12 [6].

Anatomical context of Vascular Neoplasms


Gene context of Vascular Neoplasms


Analytical, diagnostic and therapeutic context of Vascular Neoplasms

  • Hence, we use CD31 and type IV collagen in cases of presumed vascular neoplasms, adding other markers to the panel in accordance with the differential diagnosis, as well as in the recognition of compromised endothelia, such as in vascular invasion by various malignant neoplasms [11].


  1. The human hematopoietic progenitor cell antigen (CD34) in vascular neoplasia. Traweek, S.T., Kandalaft, P.L., Mehta, P., Battifora, H. Am. J. Clin. Pathol. (1991) [Pubmed]
  2. Utility of the immunohistochemical detection of FLI-1 expression in round cell and vascular neoplasm using a monoclonal antibody. Rossi, S., Orvieto, E., Furlanetto, A., Laurino, L., Ninfo, V., Dei Tos, A.P. Mod. Pathol. (2004) [Pubmed]
  3. Diagnosis and staging of hepatocellular carcinoma. Talwalkar, J.A., Gores, G.J. Gastroenterology (2004) [Pubmed]
  4. Detection of Kaposi's sarcoma-associated herpesvirus-like DNA sequence in angiosarcoma. McDonagh, D.P., Liu, J., Gaffey, M.J., Layfield, L.J., Azumi, N., Traweek, S.T. Am. J. Pathol. (1996) [Pubmed]
  5. Estrogen receptor beta expression in vascular neoplasia: an analysis of 53 benign and malignant cases. Deyrup, A.T., Tretiakova, M., Khramtsov, A., Montag, A.G. Mod. Pathol. (2004) [Pubmed]
  6. Expression of FKBP12 in benign and malignant vascular endothelium: an immunohistochemical study on conventional sections and tissue microarrays. Higgins, J.P., Montgomery, K., Wang, L., Domanay, E., Warnke, R.A., Brooks, J.D., van de Rijn, M. Am. J. Surg. Pathol. (2003) [Pubmed]
  7. Evaluation of anti-thrombomodulin antibody as a tumor marker for vascular neoplasms. Manning, T., Smoller, B.R., Horn, T.D., El Darouti, M., Marzouk, S., Hadidi, H.E., Ramadan, S. J. Cutan. Pathol. (2004) [Pubmed]
  8. Cytokeratin expression in epithelioid vascular neoplasms. Gray, M.H., Rosenberg, A.E., Dickersin, G.R., Bhan, A.K. Hum. Pathol. (1990) [Pubmed]
  9. Expression of Fli-1, a nuclear transcription factor, distinguishes vascular neoplasms from potential mimics. Folpe, A.L., Chand, E.M., Goldblum, J.R., Weiss, S.W. Am. J. Surg. Pathol. (2001) [Pubmed]
  10. Cutaneous vascular proliferations. Part III. Malignant neoplasms, other cutaneous neoplasms with significant vascular component, and disorders erroneously considered as vascular neoplasms. Requena, L., Sangueza, O.P. J. Am. Acad. Dermatol. (1998) [Pubmed]
  11. The use of CD31 and collagen IV as vascular markers. A study of 56 vascular lesions. Schmidt, D., von Hochstetter, A.R. Pathol. Res. Pract. (1995) [Pubmed]
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