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MeSH Review:

Petrosia

Giovine, M. et al., Nishimura, S. et al., Ohta, E. et al., Loya, S. et al., Choi, H.J. et al., et al.

Choi, Bae, Kim, Jung, Choi, Giner, Gunasekera, Pomponi, Giovine, Pozzolini, Favre, Bavestrello, Cerrano, Ottaviani, Chiarantini, Cerasi, Cangiotti, Zocchi, Scarfì, Sarà, Benatti,

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High impact information on Petrosia

Polyacetylenetriol (PAT), a natural marine product from the Mediterranean sea sponge Petrosia sp., was found to be a novel general potent inhibitor of DNA polymerases [1].
The NOS activity was evidenced evaluating the conversion of radioactive citrulline from [(14)C]arginine in intact cells from two different species that are phylogenetically unrelated in the class of Demospongiae: Axinella polypoides and Petrosia ficiformis [2].
The marine sponge Petrosia weinbergi was found to contain isofucosterol and clionasterol as its major sterols [3].
Minor and trace sterols from marine invertebrates 56. Novel coprostanols from the marine sponge Petrosia ficiformis [4].
Minor and trace sterols in marine invertebrates XVII. (24R)-24,26-Dimethylcholesta-5,26-dien-3 beta-OL, a new sterol from the sponge Petrosia ficiformis [5].

Anatomical context of Petrosia

Dideoxypetrosynol A, a polyacetylene from the sponge Petrosia sp., is known to exhibit significant selective cytotoxicity against several human tumor cell lines [6].
Theonellapeptolide Ie (Tp), an oligopeptide lactone isolated from a marine sponge, Petrosia sp., was shown to induce an unprecedented morphological change in the immature oocytes of the starfish Asterina pectinifera [7].

Associations of Petrosia with chemical compounds

Dihydrotubastrines: phenethylguanidine analogues from the Indo-Pacific marine sponge Petrosia cf. contignata [8].
New acetylenic enol ethers of glycerol from the sponge Petrosia sp [9].
Lembehsterols A and B, novel sulfated sterols inhibiting thymidine phosphorylase, from the marine sponge Petrosia strongylata [10].
Two new polyacetylenic acids, corticatic acids D (2) and E (3), have been isolated from the marine sponge Petrosia corticata along with the known corticatic acid A (1) as geranylgeranyltransferase type I (GGTase I) inhibitors [11].
Inhibition of membrane transport ATPases by halenaquinol, a natural cardioactive pentacyclic hydroquinone from the sponge Petrosia seriata [12].

References

Mode of inhibition of HIV-1 reverse transcriptase by polyacetylenetriol, a novel inhibitor of RNA- and DNA-directed DNA polymerases. Loya, S., Rudi, A., Kashman, Y., Hizi, A. Biochem. J. (2002) [Pubmed]
Heat stress-activated, calcium-dependent nitric oxide synthase in sponges. Giovine, M., Pozzolini, M., Favre, A., Bavestrello, G., Cerrano, C., Ottaviani, F., Chiarantini, L., Cerasi, A., Cangiotti, M., Zocchi, E., Scarfì, S., Sarà, M., Benatti, U. Nitric Oxide (2001) [Pubmed]
Sterols of the marine sponge Petrosia weinbergi: implications for the absolute configurations of the antiviral orthoesterols and weinbersterols. Giner, J.L., Gunasekera, S.P., Pomponi, S.A. Steroids (1999) [Pubmed]
Minor and trace sterols from marine invertebrates 56. Novel coprostanols from the marine sponge Petrosia ficiformis. Seidel, S.B., Proudfoot, J.R., Djerassi, C., Sica, D., Sodano, G. Steroids (1986) [Pubmed]
Minor and trace sterols in marine invertebrates XVII. (24R)-24,26-Dimethylcholesta-5,26-dien-3 beta-OL, a new sterol from the sponge Petrosia ficiformis. Khalil, M.W., Djerassi, C., Sica, D. Steroids (1980) [Pubmed]
Induction of apoptosis by dideoxypetrosynol A, a polyacetylene from the sponge Petrosia sp., in human skin melanoma cells. Choi, H.J., Bae, S.J., Kim, N.D., Jung, J.H., Choi, Y.H. Int. J. Mol. Med. (2004) [Pubmed]
Malformation of immature starfish oocytes by theonellapeptolide Ie, a Tridecapeptide lactone from a marine sponge Petrosia species, through disturbance of cortical F-actin distribution. Ohta, E., Okada, H., Ohta, S., Kobayashi, M., Kitagawa, I., Horiike, S., Takahashi, T., Hosoya, H., Yamamoto, K., Ikegami, S. Biosci. Biotechnol. Biochem. (2003) [Pubmed]
Dihydrotubastrines: phenethylguanidine analogues from the Indo-Pacific marine sponge Petrosia cf. contignata. Sperry, S., Crews, P. J. Nat. Prod. (1998) [Pubmed]
New acetylenic enol ethers of glycerol from the sponge Petrosia sp. Seo, Y., Cho, K.W., Lee, H.S., Rho, J.R., Shin, J. J. Nat. Prod. (1999) [Pubmed]
Lembehsterols A and B, novel sulfated sterols inhibiting thymidine phosphorylase, from the marine sponge Petrosia strongylata. Aoki, S., Naka, Y., Itoh, T., Furukawa, T., Rachmat, R., Akiyama, S., Kobayashi, M. Chem. Pharm. Bull. (2002) [Pubmed]
Corticatic acids D and E, polyacetylenic geranylgeranyltransferase type I inhibitors, from the marine sponge Petrosia corticata. Nishimura, S., Matsunaga, S., Shibazaki, M., Suzuki, K., Harada, N., Naoki, H., Fusetani, N. J. Nat. Prod. (2002) [Pubmed]
Inhibition of membrane transport ATPases by halenaquinol, a natural cardioactive pentacyclic hydroquinone from the sponge Petrosia seriata. Gorshkova, I.A., Gorshkov, B.A., Fedoreev, S.A., Shestak, O.P., Novikov, V.L., Stonik, V.A. Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. (1999) [Pubmed]

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