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Chemical Compound Review

ACETYLENE     ethyne

Synonyms: Acetylen, Azetylen, Narcylen, Vinylene, Ethenylene, ...
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Disease relevance of acetylene


High impact information on acetylene


Biological context of acetylene


Anatomical context of acetylene


Associations of acetylene with other chemical compounds


Gene context of acetylene

  • Gymnasterkoreayne G, a new inhibitory polyacetylene against NFAT transcription factor from Gymnaster koraiensis [17].
  • AFM snapshots of synthetic multifunctional pores with polyacetylene blockers: pseudorotaxanes and template effects [18].

Analytical, diagnostic and therapeutic context of acetylene

  • Ethanol extract showed by HPLC the presence of several peaks for polyacetylene and flavonoids, compounds corresponding to quercetin-3,3'-dimethoxy-7-0-rhamnoglucopyranose and the acetylene 1-phenyl-1,3-diyn-5-en-7-ol-acetate, previously identified in this extract [19].


  1. Lembehyne A, a spongean polyacetylene, induces neuronal differentiation in neuroblastoma cell. Aoki, S., Matsui, K., Takata, T., Hong, W., Kobayashi, M. Biochem. Biophys. Res. Commun. (2001) [Pubmed]
  2. Petrotetrayndiol A induces cell cycle arrest and apoptosis in SK-MEL-2 human melanoma cells through cytochrome c-mediated activation of caspases. Choi, H.J., Yee, S.B., Park, S.E., Im, E., Jung, J.H., Chung, H.Y., Choi, Y.H., Kim, N.D. Cancer Lett. (2006) [Pubmed]
  3. Polyacetylenes from a marine sponge Petrosia sp. inhibit DNA replication at the level of initiation. Kim, D.K., Lee, M.Y., Lee, H.S., Lee, D.S., Lee, J.R., Lee, B.J., Jung, J.H. Cancer Lett. (2002) [Pubmed]
  4. Biological activity of secondary metabolites from Bupleurum salicifolium (Umbelliferae). González, J.A., Estévez-Braun, A., Estévez-Reyes, R., Bazzocchi, I.L., Moujir, L., Jimenez, I.A., Ravelo, A.G., González, A.G. Experientia (1995) [Pubmed]
  5. Polarons in DNA. Conwell, E.M., Rakhmanova, S.V. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  6. Enantioselective esterification of prochiral phosphonate pendants of a polyphenylacetylene assisted by macromolecular helicity: storage of a dynamic macromolecular helicity memory. Onouchi, H., Miyagawa, T., Furuko, A., Maeda, K., Yashima, E. J. Am. Chem. Soc. (2005) [Pubmed]
  7. Inhibition of cyclooxygenase-2 and telomerase activities in human leukemia cells by dideoxypetrosynol A, a polyacetylene from the marine sponge Petrosia sp. Park, C., Jung, J.H., Kim, N.D., Choi, Y.H. Int. J. Oncol. (2007) [Pubmed]
  8. Polyacetylene analogs, isolated from hairy roots of Panax ginseng, inhibit Acyl-CoA : cholesterol acyltransferase. Kwon, B.M., Ro, S.H., Kim, M.K., Nam, J.Y., Jung, H.J., Lee, I.R., Kim, Y.K., Bok, S.H. Planta Med. (1997) [Pubmed]
  9. Induction of apoptosis by dideoxypetrosynol A, a polyacetylene from the sponge Petrosia sp., in human skin melanoma cells. Choi, H.J., Bae, S.J., Kim, N.D., Jung, J.H., Choi, Y.H. Int. J. Mol. Med. (2004) [Pubmed]
  10. Suppression of U937 human monocytic leukemia cell growth by dideoxypetrosynol A, a polyacetylene from the sponge Petrosia sp., via induction of Cdk inhibitor p16 and down-regulation of pRB phosphorylation. Park, C., Kim, G.Y., Kim, G.D., Lee, W.H., Cheong, J.H., Kim, N.D., Bae, S.J., Jung, J.H., Choi, Y.H. Oncol. Rep. (2006) [Pubmed]
  11. Rapid fabrication of three-dimensional porous films with biomimetic patterns by natural evaporation of amphiphilic polyacetylene solutions under ambient conditions. Salhi, F., Cheuk, K.K., Sun, Q., Lam, J.W., Cha, J.A., Li, G., Li, B., Luo, J., Chen, J., Tang, B.Z. Journal of nanoscience and nanotechnology. (2001) [Pubmed]
  12. A Comparative Study on Essential Oil Components of Wild and Cultivated Atractylodes lancea and A. chinensis. Takeda, O., Miki, E., Terabayashi, S., Okada, M., Lu, Y., He, H.S., He, S.A. Planta Med. (1996) [Pubmed]
  13. Effects of the polyacetylene capillin on human tumour cell lines. Whelan, L.C., Ryan, M.F. Anticancer Res. (2004) [Pubmed]
  14. Polyacetylene glycosides from Pratia nummularia cultures. Ishimaru, K., Osabe, M., Yan, L., Fujioka, T., Mihashi, K., Tanaka, N. Phytochemistry (2003) [Pubmed]
  15. Use of on-flow LC/1H NMR for the study of an antioxidant fraction from Orophea enneandra and isolation of a polyacetylene, lignans, and a tocopherol derivative. Cavin, A., Potterat, O., Wolfender, J.L., Hostettmann, K., Dyatmyko, W. J. Nat. Prod. (1998) [Pubmed]
  16. Bioactive constituents of Artemisia monosperma. Stavri, M., Ford, C.H., Bucar, F., Streit, B., Hall, M.L., Williamson, R.T., Mathew, K.T., Gibbons, S. Phytochemistry (2005) [Pubmed]
  17. Gymnasterkoreayne G, a new inhibitory polyacetylene against NFAT transcription factor from Gymnaster koraiensis. Dat, N.T., Cai, X.F., Shen, Q., Lee, I.S., Lee, E.J., Park, Y.K., Bae, K., Kim, Y.H. Chem. Pharm. Bull. (2005) [Pubmed]
  18. AFM snapshots of synthetic multifunctional pores with polyacetylene blockers: pseudorotaxanes and template effects. Kumaki, J., Yashima, E., Bollot, G., Mareda, J., Litvinchuk, S., Matile, S. Angew. Chem. Int. Ed. Engl. (2005) [Pubmed]
  19. New evidences of antimalarial activity of Bidens pilosa roots extract correlated with polyacetylene and flavonoids. Oliveira, F.Q., Andrade-Neto, V., Krettli, A.U., Brandão, M.G. Journal of ethnopharmacology. (2004) [Pubmed]
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