High impact information on Axinella

• In Axinella polypoides (Demospongiae, Axinellidae), ADP-ribosyl cyclase was activated by temperature increases by means of an abscisic acid-induced, protein kinase A-dependent mechanism [1].
• Of two galactose-binding hemagglutinins isolated from the sponge Axinella polypoides, axinella I was strongly mitogenic for human peripheral blood lymphocytes, and axinella II was not [2].
• Axinelloside A, an unprecedented highly sulfated lipopolysaccharide inhibiting telomerase, from the marine sponge, Axinella infundibula [3].
• The ethyl acetate extract of Penicillium sp., derived from the Mediterranean sponge Axinella verrucosa, yielded the known compound communesin B (1) and its new congeners communesins C (2) and D (3), as well as the known compounds griseofulvin, dechlorogriseofulvin, and oxaline [4].
• Four new sterols have been isolated from the marine sponge Axinella cf. bidderi, 17alpha-hydroxy-22,23-epoxy-24-methylcholest-5-en-3beta-ol (1) and 17alpha-hydroxy-22,23-epoxycholest-5-en-3beta-ol (2), together with 3 and 4, which possess respectively the cholestene and the cholestane skeleton with a cyclic enol ether linkage between C-18 and C-22 [5].

Biological context of Axinella

• Amino acid sequence of the D-galactose binding lectin II from the sponge Axinella polypoides (Schmidt) and identification of the carbohydrate binding site in lectin II and related lectin I [6].

Associations of Axinella with chemical compounds

• Four new bioactive pyrrole-derived alkaloids from the marine sponge Axinella brevistyla [7].
• From the marine sponge Axinella carteri, the new 3-bromopyrrole carboxylic acid derivative, 5, was obtained along with the known compounds aldisin (6) and 2-bromoaldisin (7) [8].
• A new diterpene, N-formyl-7-amino-11-cycloamphilectene (1), was isolated from the apolar extract of the Vanuatu sponge Axinella sp. The structure and relative stereochemistry were established by spectroscopic and single-crystal X-ray studies [9].
• However, aqueous extracts of Stylotella aurantium and Axinella carteri collected in Yap State, Micronesia, afforded a known N-methyl-d-aspartic acid (NMDA)-type glutamate receptor agonist, (2S,4S)-4-sulfooxypiperidine-2-carboxylic acid (2), as a common active principle [10].
• Metabolism in porifera-V. Biosynthesis of 19-nor-stanols: conversion of cholesterol into 19-nor-cholestanols by the sponge Axinella polypoides [11].

Analytical, diagnostic and therapeutic context of Axinella

• The distribution of the two D-galactose-specific lectins within the sponge tissue of Axinella polypoides was studied by autoradiography and by an immunohistochemical method on paraplast- and cryosections [12].

References