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MeSH Review

Influenza A Virus, H3N8 Subtype

 
 
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Disease relevance of Influenza A Virus, H3N8 Subtype

 

High impact information on Influenza A Virus, H3N8 Subtype

  • The corresponding sequence of the NP of an equine influenza virus, A/Eq/Prague/56, which has a substitution (leucine to proline) at position 283, was not recognized by the lymph node cells from mice primed with either A/Okuda or A/Eq/Prague [5].
  • Experimental infection of ponies with equine influenza A2 (H3N8) virus strains of different pathogenicity elicits varying interferon and interleukin-6 responses [6].
  • Triton X-100-solubilized membrane glycoproteins (neuraminidase and hemagglutinin) from purified equine influenza virus particles were separated by column displacement electrophoresis (isotachophoresis) in the presence of Pharmalyte spacers [7].
  • No significant increase of hemagglutination-inhibition antibody titers to subtypes 1 and 2 of equine influenza virus were detected in any of the sera tested [8].
 

Gene context of Influenza A Virus, H3N8 Subtype

References

  1. Attenuation of equine influenza viruses through truncations of the NS1 protein. Quinlivan, M., Zamarin, D., García-Sastre, A., Cullinane, A., Chambers, T., Palese, P. J. Virol. (2005) [Pubmed]
  2. Efficacy of equine influenza vaccines for protection against A/Equine/Jilin/89 (H3N8)--a new equine influenza virus. Webster, R.G., Thomas, T.L. Vaccine (1993) [Pubmed]
  3. Defective influenza A virus generated entirely from plasmids: its RNA is expressed in infected mouse lung and modulates disease. Duhaut, S.D., Dimmock, N.J. J. Virol. Methods (2003) [Pubmed]
  4. Safety and immunogenicity of recombinants based on the genetically-engineered vaccinia strain, NYVAC. Tartaglia, J., Cox, W.I., Pincus, S., Paoletti, E. Dev. Biol. Stand. (1994) [Pubmed]
  5. A dominant Th epitope in influenza nucleoprotein. Analysis of the fine specificity and functional repertoire of T cells recognizing a single determinant. Gao, X.M., Liew, F.Y., Tite, J.P. J. Immunol. (1990) [Pubmed]
  6. Experimental infection of ponies with equine influenza A2 (H3N8) virus strains of different pathogenicity elicits varying interferon and interleukin-6 responses. Wattrang, E., Jessett, D.M., Yates, P., Fuxler, L., Hannant, D. Viral Immunol. (2003) [Pubmed]
  7. Separation of hemagglutinin and neuraminidase from influenza virus membrane by column displacement electrophoresis (isotachophoresis) with preservation of their activities. Johansson, G., Abusugra, I., Lövgren, K., Morein, B. Prep. Biochem. (1988) [Pubmed]
  8. Antibody responses of horses to equine influenza viruses during a postepizootic period in Japan. Goto, H., Shimizu, K., Taya, Y., Noda, H., Tokunaga, T. Can. J. Comp. Med. (1982) [Pubmed]
 
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