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MeSH Review

Sex Preselection

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High impact information on Sex Preselection


Associations of Sex Preselection with chemical compounds

  • This paper will examine the recent Human Fertilisation and Embryology Authority public consultation on sex selection [6].
  • The recent report of the House of Commons' Select Committee on Science and Technology (House of Commons, 2005) states that the UK should carefully consider the impact of sex selection on other countries before an attempt is made to change or modify the legislation in UK [7].

Gene context of Sex Preselection

  • Sex preselection that is based on flow-cytometric measurement of sperm DNA content to enable sorting of X- from Y-chromosome-bearing sperm has proven reproducible at various locations and with many species at greater than 90% purity [8].
  • Two reasons are given: 1) Prima facie examination of any argument for sex selection cannot overcome the unfair and sexist basis of a choice to select the sex of a child [9].
  • In spite of the general impression that, at present, no reliable technique with clearly known probabilities of success and failure is available, this goal seems to be at close reach and sex selection of children will certainly become accessible in a not very remote future." (SUMMARY IN FRE AND ITA)[10]

Analytical, diagnostic and therapeutic context of Sex Preselection


  1. Influence of porcine spermadhesins on the susceptibility of boar spermatozoa to high dilution. Centurion, F., Vazquez, J.M., Calvete, J.J., Roca, J., Sanz, L., Parrilla, I., Garcia, E.M., Martinez, E.A. Biol. Reprod. (2003) [Pubmed]
  2. Female sex selection using clomiphene citrate and albumin separation of human sperm. Silverman, A.Y., Stephens, S.R., Drouin, M.T., Zack, R.G., Osborne, J., Ericsson, S.A. Hum. Reprod. (2002) [Pubmed]
  3. New advances in sex preselection. Reubinoff, B.E., Schenker, J.G. Fertil. Steril. (1996) [Pubmed]
  4. Prenatal sex determination and selection. Shushan, A., Schenker, J.G. Hum. Reprod. (1993) [Pubmed]
  5. Male to female ratio after gonadotropin-induced ovulation. Ben-Rafael, Z., Matalon, A., Blankstein, J., Serr, D.M., Lunenfeld, B., Mashiach, S. Fertil. Steril. (1986) [Pubmed]
  6. Sex selection, child welfare and risk: a critique of the HFEA's recommendations on sex selection. Tizzard, J. Health care analysis : HCA : journal of health philosophy and policy. (2004) [Pubmed]
  7. Are we talking about the butterflies or a butterfly effect? Comment on 'No country is an island'. Kahraman, S. Reprod. Biomed. Online (2005) [Pubmed]
  8. Sex preselection: high-speed flow cytometric sorting of X and Y sperm for maximum efficiency. Johnson, L.A., Welch, G.R. Theriogenology (1999) [Pubmed]
  9. Is sex selection ethical? Fletcher, J.C. Prog. Clin. Biol. Res. (1983) [Pubmed]
  10. A note on the state of the art of preselection of the sex of children. Muhsam, H.V. Genus. (1987) [Pubmed]
  11. The clinical relevance of sex selection techniques. Zarutskie, P.W., Muller, C.H., Magone, M., Soules, M.R. Fertil. Steril. (1989) [Pubmed]
  12. Preimplantation genetic diagnosis for elective sex selection, the IVF market economy, and the child--another long day's journey into night? Sills, E.S., Palermo, G.D. J. Assist. Reprod. Genet. (2002) [Pubmed]
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