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Chemical Compound Review

Authority     N-[2,4-dichloro-5-[4- (difluoromethyl)-3...

Synonyms: Sulfentrazone, Sulfentrazone;, SureCN44683, HSDB 7014, LS-90107, ...
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Disease relevance of F 6285

  • The prevalence at school age of cerebral palsy and severe education subnormality in children of low birthweight (less than or equal to 4 lb=1814 g) born to residents in the region served by the South East Thames Regional Health Authority in the early 1970s was compared with that in children of the same birthweight born in 1950-53 [1].
  • METHODS: General practitioners and/or hospital consultants in the Norwich Health Authority, Norfolk, UK, notified the Norfolk Arthritis Register (NOAR) of all patients who had onset of inflammatory polyarthritis (swelling of > or =2 joints) during 1990 [2].
  • DESIGN: All AIDS cases diagnosed from 1 January 1982 to 1 August 1989 in Riverside Health Authority were identified from a local register of HIV infection and cross-checked against records of AIDS cases reported to the national AIDS surveillance system [3].
  • We surveyed the clinical presentation, initial management and subsequent course of a prospectively registered, population-based cohort of 230 patients with Type 1 (insulin-dependent) diabetes mellitus diagnosed before age 21 years in the Oxford Regional Health Authority area in 1985 and 1986 [4].
  • SETTING: Hospital-based HIV clinics within the Riverside District Health Authority in London. PATIENTS: Patients (total, 1415) with AIDS (n = 476), symptomatic (n = 687) or asymptomatic (n = 194) HIV-1 infection, or of unknown clinical status (n = 58), who first received ZDV between June 1986 and October 1991 [5].

Psychiatry related information on F 6285


High impact information on F 6285


Chemical compound and disease context of F 6285


Biological context of F 6285

  • The recurrence of neural tube defects (NTD) in the sib following the index case of all patients who consulted the South-East Thames Regional Health Authority Genetics Centre in the period 1972 to mid-1979 was calculated [21].
  • The study is based on a collaboration between the Cancer Registry of Norway, the Norwegian Radiation Protection Authority, and National Radiological Protection Board (NRPB, UK) [22].
  • Data were collected over a 3 month period using a prospective questionnaire survey of general practitioners, who submitted and received a mid-stream urine (MSU) result from selected microbiology laboratories in England and Wales. In addition, prescribing analyses and cost (PACT) data were requested from the Prescription Prescribing Authority [23].
  • AIMS: To ascertain the causes of deaths among a very large cohort of heroin injecting drug users (IDUs) who, from 1985 to 1998, attended 36 Public Health Authority Centres for Drug Users (PCDUs) in north-eastern Italy [24].
  • Environmental monitoring of nitrous oxide and volatile agents was carried out between August 1996 and October 1997 within operating theatre areas in eight hospitals within the Bro Taf Health Authority [25].

Anatomical context of F 6285

  • Its use as an intravenous infusion is Federal Drug Authority (USA) approved for the enhancement of myeloid recovery following autologous bone-marrow transplantation [26].
  • Changing incidence and geographical distribution of malignant paediatric germ cell tumours in the West Midlands Health Authority region, 1957-92 [27].
  • Reasons for these findings are discussed in the light of the Human Fertilisation and Embryology Authority regulations relating to semen donation [28].
  • METHODS: Administrative data were used to identify patients who underwent coronary artery bypass grafting (CABG), including those who had combined CABG and valve procedures, and patients who underwent percutaneous transluminal angioplasty (PTCA) in the Calgary Regional Health Authority from July 1994 to March 1998 [29].
  • Twenty-five national kabaddi players (Asiad gold medalists 1990), mean age 27.91 years, who attended a national camp at the Sports Authority of India, Bangalore before the Beijing Asian Games in 1990, were investigated for their physical characteristics, body fat, lean body mass (LBM) and somatotype [30].

Associations of F 6285 with other chemical compounds


Gene context of F 6285

  • A study of the spectrum of beta-thalassemia mutations in the southern part of the West Bank of the Palestinian Authority revealed the presence of 10 different beta-globin mutations [36].
  • CONCLUSIONS: This study shows that the management of children with ADHD in Wirral Health Authority is compatible with NICE guidance [37].
  • Within the counties administered by the Oxford Regional Health Authority (population 2 328 100) the prevalence of tuberous sclerosis was estimated as 1 in 29 900 for persons under 65 years of age [38].
  • METHODS--Data on hospital admissions for acute respiratory conditions were obtained by electoral ward from the West Midlands Regional Health Authority Information Department Körner inpatient data including asthma (ICD 493) and all acute respiratory disease (466, 480-486, 490-496) for the period April 1988 to March 1990 [39].
  • Antibiotic policies--relevance to general practitioner prescribing. Family Health Services Authority, Great Britain [40].

Analytical, diagnostic and therapeutic context of F 6285

  • A cross-sectional survey of 7500 households in the Wycombe Health Authority area and the same number of randomly-selected households nationwide was followed up by interviews of positive respondents from the Wycombe Health Authority area [41].
  • We compared the ICU mortality rate in children from the area the Trent Health Authority, UK, with the rate in children from Victoria, Australia, where paediatric intensive care is highly centralised [42].
  • Between January, 1969, and December, 1973, 2058 truncal vagotomies were performed in the Merseyside Regional Health Authority area [43].
  • METHODS: Population-based case-control study in Norfolk, England, involving adult patients, ages 18-70, with an inflammatory polyarthritis of <12 months' duration who were recruited from the Norfolk Arthritis Register. Controls, matched for sex and date of birth, were selected from the primary care register of the Norwich Health Authority [44].
  • Therefore, a cohort study over a period of 12 yr (1985 to 1997) in 3499 employees of the Electric Generation Authority of Thailand, aged 35 to 55 yr, was conducted to determine the prevalence of decreased kidney function and risk factors associated with future development of decreased kidney function [45].


  1. Cerebral palsy and severe educational subnormality in low-birthweight children: a comparison of births in 1951-53 and 1970-73. Alberman, E., Benson, J., McDonald, A. Lancet (1982) [Pubmed]
  2. Estimating the incidence of rheumatoid arthritis: trying to hit a moving target? Wiles, N., Symmons, D.P., Harrison, B., Barrett, E., Barrett, J.H., Scott, D.G., Silman, A.J. Arthritis Rheum. (1999) [Pubmed]
  3. AIDS surveillance: a direct assessment of under-reporting. Hickman, M., Aldous, J., Gazzard, B., Ellam, A. AIDS (1993) [Pubmed]
  4. Presentation and progress of childhood diabetes mellitus: a prospective population-based study. The Bart's-Oxford Study Group. Pinkey, J.H., Bingley, P.J., Sawtell, P.A., Dunger, D.B., Gale, E.A. Diabetologia (1994) [Pubmed]
  5. Rate of CD4 cell decline and prediction of survival in zidovudine-treated patients. Easterbrook, P.J., Emami, J., Gazzard, B. AIDS (1993) [Pubmed]
  6. Guidance for commissioners on the cost effectiveness of smoking cessation interventions. Health Educational Authority. Parrott, S., Godfrey, C., Raw, M., West, R., McNeill, A. Thorax (1998) [Pubmed]
  7. Child and adolescent inpatient restraint reduction: a state initiative to promote strength-based care. LeBel, J., Stromberg, N., Duckworth, K., Kerzner, J., Goldstein, R., Weeks, M., Harper, G., LaFlair, L., Sudders, M. Journal of the American Academy of Child and Adolescent Psychiatry. (2004) [Pubmed]
  8. A cluster-analytic investigation of MMPI profiles of serious male and female juvenile offenders. Espelage, D.L., Cauffman, E., Broidy, L., Piquero, A.R., Mazerolle, P., Steiner, H. Journal of the American Academy of Child and Adolescent Psychiatry. (2003) [Pubmed]
  9. HIV infection and risk behaviors among male port workers in Santos, Brazil. Larcerda, R., Stall, R., Gravato, N., Tellini, R., Hudes, E.S., Hearst, N. American journal of public health. (1996) [Pubmed]
  10. Death certification after a diagnosis of presenile dementia. Newens, A.J., Forster, D.P., Kay, D.W. Journal of epidemiology and community health. (1993) [Pubmed]
  11. Fetal death and congenital malformation in babies born to nuclear industry employees: report from the nuclear industry family study. Doyle, P., Maconochie, N., Roman, E., Davies, G., Smith, P.G., Beral, V. Lancet (2000) [Pubmed]
  12. Factors that affect outcome of in-vitro fertilisation treatment. Templeton, A., Morris, J.K., Parslow, W. Lancet (1996) [Pubmed]
  13. The Y chromosome pool of Jews as part of the genetic landscape of the Middle East. Nebel, A., Filon, D., Brinkmann, B., Majumder, P.P., Faerman, M., Oppenheim, A. Am. J. Hum. Genet. (2001) [Pubmed]
  14. Association of the platelet Pl(A) polymorphism of glycoprotein IIb/IIIa and the fibrinogen Bbeta 448 polymorphism with myocardial infarction and extent of coronary artery disease. Carter, A.M., Ossei-Gerning, N., Wilson, I.J., Grant, P.J. Circulation (1997) [Pubmed]
  15. Reducing community dyspepsia drug costs: a controlled trial. Valori, R.M., Brown, C.M., Strangeways, P., Bradburn, M. Gut (2001) [Pubmed]
  16. The prevalence of multiple sclerosis in the Southampton and South West Hampshire Health Authority. Roberts, M.H., Martin, J.P., McLellan, D.L., McIntosh-Michaelis, S.A., Spackman, A.J. J. Neurol. Neurosurg. Psychiatr. (1991) [Pubmed]
  17. Trilateral retinoblastoma. A report of five patients. Amoaku, W.M., Willshaw, H.E., Parkes, S.E., Shah, K.J., Mann, J.R. Cancer (1996) [Pubmed]
  18. A cross-sectional analysis of acute hepatitis B virus reported to the Vancouver Coastal Health Authority from 2000 to 2003. Leung, Y., Chan, J.I., Yoshida, E., Wu, H.X., Daly, P.C. Can. J. Gastroenterol. (2006) [Pubmed]
  19. Lung cancer and passive smoking at work: the Carroll case. Woodward, S.D., Winstanley, M.H. Med. J. Aust. (1990) [Pubmed]
  20. Dietary intake of organotin compounds in Finland: a market-basket study. Rantakokko, P., Kuningas, T., Saastamoinen, K., Vartiainen, T. Food additives and contaminants. (2006) [Pubmed]
  21. Recurrence risks for neural tube defects in a genetic counseling clinic population. Seller, M.J. J. Med. Genet. (1981) [Pubmed]
  22. Residential radon exposure and lung cancer--an epidemiological study of Norwegian municipalities. Magnus, K., Engeland, A., Green, B.M., Haldorsen, T., Muirhead, C.R., Strand, T. Int. J. Cancer (1994) [Pubmed]
  23. Laboratory antibiotic susceptibility reporting and antibiotic prescribing in general practice. Tan, T.Y., McNulty, C., Charlett, A., Nessa, N., Kelly, C., Beswick, T. J. Antimicrob. Chemother. (2003) [Pubmed]
  24. Study of 2708 heroin-related deaths in north-eastern Italy 1985-98 to establish the main causes of death. Quaglio, G., Talamini, G., Lechi, A., Venturini, L., Lugoboni, F., Mezzelani, P. Addiction (2001) [Pubmed]
  25. An environmental survey of compliance with Occupational Exposure Standards (OES) for anaesthetic gases. Henderson, K.A., Matthews, I.P. Anaesthesia. (1999) [Pubmed]
  26. The use of granulocyte-macrophage colony-stimulating factor to enhance hematologic parameters of patients with cirrhosis and hypersplenism. Gurakar, A., Fagiuoli, S., Gavaler, J.S., Hassanein, T., Jabbour, N., Wright, H.I., Deal, S.A., Shah, A., Brown, M., Carr, B.I. J. Hepatol. (1994) [Pubmed]
  27. Changing incidence and geographical distribution of malignant paediatric germ cell tumours in the West Midlands Health Authority region, 1957-92. Muir, K.R., Parkes, S.E., Lawson, S., Thomas, A.K., Cameron, A.H., Mann, J.R. Br. J. Cancer (1995) [Pubmed]
  28. A survey of semen donation: phase I--the view of UK licensed centres. Golombok, S., Cook, R. Hum. Reprod. (1994) [Pubmed]
  29. A case study of hospital closure and centralization of coronary revascularization procedures. Hemmelgarn, B.R., Ghali, W.A., Quan, H. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. (2001) [Pubmed]
  30. Morphological and physiological studies on Indian national kabaddi players. Dey, S.K., Khanna, G.L., Batra, M. British journal of sports medicine. (1993) [Pubmed]
  31. Natural rubber latex allergy among health care workers: a systematic review of the evidence. Bousquet, J., Flahault, A., Vandenplas, O., Ameille, J., Duron, J.J., Pecquet, C., Chevrie, K., Annesi-Maesano, I. J. Allergy Clin. Immunol. (2006) [Pubmed]
  32. Clinical efficacy of bupropion in the management of smoking cessation. Jorenby, D. Drugs (2002) [Pubmed]
  33. The incidence of adverse events and risk factors for upper gastrointestinal disorders associated with meloxicam use amongst 19,087 patients in general practice in England: cohort study. Martin, R.M., Biswas, P., Mann, R.D. British journal of clinical pharmacology. (2000) [Pubmed]
  34. Diltiazem co-treatment in renal transplant patients receiving microemulsion cyclosporin. Kumana, C.R., Tong, M.K., Li, C.S., Lauder, I.J., Lee, J.S., Kou, M., Walley, T., Haycox, A., Chan, T.M. British journal of clinical pharmacology. (2003) [Pubmed]
  35. Management of angina pectoris in general practice: a questionnaire survey of general practitioners. Gandhi, M.M., Lampe, F.C., Wood, D.A. The British journal of general practice : the journal of the Royal College of General Practitioners. (1995) [Pubmed]
  36. The beta+-IVS-I-6 (T-->C) mutation accounts for half of the thalassemia chromosomes in the Palestinian populations of the mountain regions. El-Latif, M.A., Filon, D., Rund, D., Oppenheim, A., Kanaan, M. Hemoglobin (2002) [Pubmed]
  37. Current practice in the management of Attention Deficit Disorder with Hyperactivity (ADHD). Parr, J.R., Ward, A., Inman, S. Child: care, health and development. (2003) [Pubmed]
  38. Tuberous sclerosis: a new estimate of prevalence within the Oxford region. Hunt, A., Lindenbaum, R.H. J. Med. Genet. (1984) [Pubmed]
  39. Hospital admission rates for asthma and respiratory disease in the West Midlands: their relationship to air pollution levels. Walters, S., Phupinyokul, M., Ayres, J. Thorax (1995) [Pubmed]
  40. Antibiotic policies--relevance to general practitioner prescribing. Family Health Services Authority, Great Britain. Swann, R.A., Clark, J. J. Antimicrob. Chemother. (1994) [Pubmed]
  41. A population study of food intolerance. Young, E., Stoneham, M.D., Petruckevitch, A., Barton, J., Rona, R. Lancet (1994) [Pubmed]
  42. Should paediatric intensive care be centralised? Trent versus Victoria. Pearson, G., Shann, F., Barry, P., Vyas, J., Thomas, D., Powell, C., Field, D. Lancet (1997) [Pubmed]
  43. IgA deficiency and severe post-vagotomy diarrhoea. McLoughlin, G.A., Bradley, J., Chapman, D.M., Temple, J.G., Hede, J.E., McFarland, J. Lancet (1976) [Pubmed]
  44. Blood transfusion, smoking, and obesity as risk factors for the development of rheumatoid arthritis: results from a primary care-based incident case-control study in Norfolk, England. Symmons, D.P., Bankhead, C.R., Harrison, B.J., Brennan, P., Barrett, E.M., Scott, D.G., Silman, A.J. Arthritis Rheum. (1997) [Pubmed]
  45. Risk factors for development of decreased kidney function in a southeast Asian population: a 12-year cohort study. Domrongkitchaiporn, S., Sritara, P., Kitiyakara, C., Stitchantrakul, W., Krittaphol, V., Lolekha, P., Cheepudomwit, S., Yipintsoi, T. J. Am. Soc. Nephrol. (2005) [Pubmed]
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