- Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver. Beuers, U., Bilzer, M., Chittattu, A., Kullak-Ublick, G.A., Keppler, D., Paumgartner, G., Dombrowski, F. Hepatology (2001)