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Chemical Compound Review

NSC-683769     (4R)-4- [(3R,5S,8S,9S,10S,13R,14S,17R) -3,7...

Synonyms: AC1L8WFY, CTK8E0426, NSC683769
 
 
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Disease relevance of URSODEOXYCHOLIC ACID

 

Psychiatry related information on URSODEOXYCHOLIC ACID

 

High impact information on URSODEOXYCHOLIC ACID

 

Chemical compound and disease context of URSODEOXYCHOLIC ACID

 

Biological context of URSODEOXYCHOLIC ACID

 

Anatomical context of URSODEOXYCHOLIC ACID

 

Associations of URSODEOXYCHOLIC ACID with other chemical compounds

 

Gene context of URSODEOXYCHOLIC ACID

 

Analytical, diagnostic and therapeutic context of URSODEOXYCHOLIC ACID

References

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  20. Metabolism, pharmacokinetics, and activity of a new 6-fluoro analogue of ursodeoxycholic acid in rats and hamsters. Roda, A., Pellicciari, R., Polimeni, C., Cerrè, C., Forti, G.C., Sadeghpour, B., Sapigni, E., Gioacchini, A.M., Natalini, B. Gastroenterology (1995) [Pubmed]
  21. Intestinal absorption of ursodeoxycholic acid in patients with extrahepatic biliary obstruction and bile drainage. Walker, S., Rudolph, G., Raedsch, R., Stiehl, A. Gastroenterology (1992) [Pubmed]
  22. Tauroursodeoxycholate increases rat liver ursodeoxycholate levels and limits lithocholate formation better than ursodeoxycholate. Rodrigues, C.M., Kren, B.T., Steer, C.J., Setchell, K.D. Gastroenterology (1995) [Pubmed]
  23. Comparative effects of ursodeoxycholic acid and chenodeoxycholic acid on bile acid kinetics and biliary lipid secretion in humans. Evidence for different modes of action on bile acid synthesis. Nilsell, K., Angelin, B., Leijd, B., Einarsson, K. Gastroenterology (1983) [Pubmed]
  24. Expression of HLA molecules on hepatocytes: does ursodeoxycholic acid prevent immunologic injury? Borum, M., Fromm, H. Gastroenterology (1990) [Pubmed]
  25. Ursodeoxycholic acid limits liver histologic alterations and portal hypertension induced by bile duct ligation in the rat. Poo, J.L., Feldmann, G., Erlinger, S., Braillon, A., Gaudin, C., Dumont, M., Lebrec, D. Gastroenterology (1992) [Pubmed]
  26. Acute effects of ursodeoxycholic and chenodeoxycholic acid on the small intestinal absorption of bile acids. Stiehl, A., Raedsch, R., Rudolph, G. Gastroenterology (1990) [Pubmed]
  27. Effect of tauroursodeoxycholic and ursodeoxycholic acid on ethanol-induced cell injuries in the human Hep G2 cell line. Neuman, M.G., Cameron, R.G., Shear, N.H., Bellentani, S., Tiribelli, C. Gastroenterology (1995) [Pubmed]
  28. The site-specific delivery of ursodeoxycholic acid to the rat colon by sulfate conjugation. Rodrigues, C.M., Kren, B.T., Steer, C.J., Setchell, K.D. Gastroenterology (1995) [Pubmed]
  29. Gallbladder motility in cholesterol gallstone disease. Effect of ursodeoxycholic acid administration and gallstone dissolution. Festi, D., Frabboni, R., Bazzoli, F., Sangermano, A., Ronchi, M., Rossi, L., Parini, P., Orsini, M., Primerano, A.M., Mazzella, G. Gastroenterology (1990) [Pubmed]
  30. Ursodeoxycholic acid and cholesterol induce enterohepatic cycling of bilirubin in rodents. Méndez-Sánchez, N., Brink, M.A., Paigen, B., Carey, M.C. Gastroenterology (1998) [Pubmed]
  31. Bile acids substituted in the 6 position prevent cholesterol gallstone formation in the hamster. Cohen, B.I., Matoba, N., Mosbach, E.H., Ayyad, N., Hakam, K., Suh, S.O., McSherry, C.K. Gastroenterology (1990) [Pubmed]
  32. An NO derivative of ursodeoxycholic acid protects against Fas-mediated liver injury by inhibiting caspase activity. Fiorucci, S., Mencarelli, A., Palazzetti, B., Del Soldato, P., Morelli, A., Ignarro, L.J. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  33. Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes. Qiao, L., Yacoub, A., Studer, E., Gupta, S., Pei, X.Y., Grant, S., Hylemon, P.B., Dent, P. Hepatology (2002) [Pubmed]
  34. Ursodeoxycholic acid modulates E2F-1 and p53 expression through a caspase-independent mechanism in transforming growth factor beta1-induced apoptosis of rat hepatocytes. Sola, S., Ma, X., Castro, R.E., Kren, B.T., Steer, C.J., Rodrigues, C.M. J. Biol. Chem. (2003) [Pubmed]
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  36. Treatment with ursodeoxycholic acid renders children with biliary atresia suitable for liver transplantation. Ullrich, D., Rating, D., Schröter, W., Hanefeld, F., Bircher, J. Lancet (1987) [Pubmed]
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  40. Serum concentrations of ursodeoxycholic acid in portal venous and systemic venous blood of fasting humans as determined by isotope dilution-mass spectrometry. Ewerth, S., Angelin, B., Einarsson, K., Nilsell, K., Björkhem, I. Gastroenterology (1985) [Pubmed]
 
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