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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Antioxidant flavan-3-ols and flavonol glycosides from Maytenus aquifolium.

TLC autographic assay revealed, in the EtOAc extract obtained from leaves and root bark of Maytenus aquifolium (Celastraceae), the presence of fi ve compounds exhibiting antioxidant properties towards beta-carotene. They were isolated and identified as epigallocatechin (1), (+) ouratea-catechin (2), proanthocyanidin (3), kaempferol 3-O-alpha-L-rhamnopyranosyl (1-->6)-O-[beta-D-glucopyranosyl (1-->3)-O-alpha-L-rhamnopyranosyl-(1-->2)]-O-beta-D-glucopyranosyl (4) and quercetin 3-O-alpha-L-rhamnopyranosyl (1-->6)-O-[beta-D-glucopyranosyl (1-->3)-O-alpha-L-rhamnopyranosyl-(1-->2)]-O-beta-D-glucopyranosyl (5). The isolates were investigated for their redox properties using cyclic voltammetry and for their radical scavenging abilities through spectrophotometric assay on the reduction of 2,2-diphenyl-pycryl hydrazyl (DPPH). These results were correlated to the inhibition of beta-carotene bleaching on TLC autographic assay and to structural features of the flavonoids.[1]


  1. Antioxidant flavan-3-ols and flavonol glycosides from Maytenus aquifolium. Corsino, J., Silva, D.H., Zanoni, M.V., da Silva Bolzani, V., França, S.C., Pereira, A.M., Furlan, M. Phytotherapy research : PTR. (2003) [Pubmed]
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