- The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance. Georgescu, D., Sears, R.M., Hommel, J.D., Barrot, M., Bolaños, C.A., Marsh, D.J., Bednarek, M.A., Bibb, J.A., Maratos-Flier, E., Nestler, E.J., DiLeone, R.J. J. Neurosci. (2005)