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Kashima, K. et al.

Katsuro Kashima, Daisuke Kawasaki, Goichi Yotsumoto, Shinsaku Hatake, Erika Yamashita, Shinya Nagayoshi, Yusuke Yoshishige, Kazuyuki Tanoue, Shinjirou Nagano, Hideki Tanaka, Norihito Nuruki, Masahiro Sonoda,

Rapid progression of aortic regurgitation with thoracic aortic aneurysm due to Takayasu arteritis associated with ulcerative colitis.

A 25-year-old woman with ulcerative colitis developed heart failure due to severe aortic regurgitation. Although chest X-ray 18 months previously showed a normal cardiac shadow, thoracic aortic aneurysm progressed due to Takayasu arteritis. Aortic valve and ascending aorta replacement were performed successfully, but re-valve replacement for severe aortic regurgitation due to prosthetic valve detachment and aortic root replacement for valsalva sinus rupture were required. Human leukocyte antigen analysis showed B35 and B52, the typical haplotype in cases with coexistence of both diseases and associated sustained inflammation. Close observation and early aortic root replacement were needed in this case.[1]

References

Rapid progression of aortic regurgitation with thoracic aortic aneurysm due to Takayasu arteritis associated with ulcerative colitis. Kashima, K., Kawasaki, D., Yotsumoto, G., Hatake, S., Yamashita, E., Nagayoshi, S., Yoshishige, Y., Tanoue, K., Nagano, S., Tanaka, H., Nuruki, N., Sonoda, M. Intern. Med. (2010) [Pubmed]

Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg