The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Aortic Valve Insufficiency

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Aortic Valve Insufficiency


High impact information on Aortic Valve Insufficiency


Chemical compound and disease context of Aortic Valve Insufficiency

  • Nitroprusside was used to reduce afterload in 13 patients with isolated, severe aortic regurgitation [11].
  • The response to afterload stress determined by angiotensin challenge and the end-systolic pressure-volume relationship was evaluated echocardiographically in 16 asymptomatic or mildly symptomatic patients with chronic severe aortic regurgitation, ages 15 to 56 years (mean 32 +/- 12) [12].
  • Ejection fraction in patients with aortic regurgitation and normal subjects were similar at rest (55 +/- 10% vs 59 +/- 6%) and were unchanged by nitroglycerin [13].
  • Observations on the optimum time for operative intervention for aortic regurgitation. II. Serial echocardiographic evaluation of asymptomatic patients [14].
  • Left ventricular (LV) apexcardiogram (ACG) and its first derivative (dA/dt) was obtained in 104 normal subjects and 34 patients with chronic aortic incompetence (AI) [15].

Biological context of Aortic Valve Insufficiency


Anatomical context of Aortic Valve Insufficiency


Gene context of Aortic Valve Insufficiency


Analytical, diagnostic and therapeutic context of Aortic Valve Insufficiency


  1. High frequency of mitral valve prolapse and aortic regurgitation among asymptomatic adults with Down's syndrome. Goldhaber, S.Z., Brown, W.D., Sutton, M.G. JAMA (1987) [Pubmed]
  2. Is standardization of left ventricular chamber elastance necessary? Hsia, H.H., Starling, M.R. Circulation (1990) [Pubmed]
  3. Transaortic closure of ventricular septal defect in patients with corrected transposition with pulmonary stenosis or atresia. Russo, P., Danielson, G.K., Driscoll, D.J. Circulation (1987) [Pubmed]
  4. Myosin isoenzyme changes in several models of rat cardiac hypertrophy. Mercadier, J.J., Lompré, A.M., Wisnewsky, C., Samuel, J.L., Bercovici, J., Swynghedauw, B., Schwartz, K. Circ. Res. (1981) [Pubmed]
  5. Evaluation of ventricular septal defect by transesophageal echocardiography: intraoperative assessment. Tee, S.D., Shiota, T., Weintraub, R., Teien, D.E., Deng, Y.B., Sahn, D.J., Omoto, R., Kyo, S. Am. Heart J. (1994) [Pubmed]
  6. An assessment of heart-valve abnormalities in obese patients taking dexfenfluramine, sustained-release dexfenfluramine, or placebo. Sustained-Release Dexfenfluramine Study Group. Weissman, N.J., Tighe, J.F., Gottdiener, J.S., Gwynne, J.T. N. Engl. J. Med. (1998) [Pubmed]
  7. Nifedipine in severe aortic regurgitation. Manyari, D.E., Yunus, A. N. Engl. J. Med. (1995) [Pubmed]
  8. Nifedipine in asymptomatic patients with severe aortic regurgitation and normal left ventricular function. Scognamiglio, R., Rahimtoola, S.H., Fasoli, G., Nistri, S., Dalla Volta, S. N. Engl. J. Med. (1994) [Pubmed]
  9. Prediction of indications for valve replacement among asymptomatic or minimally symptomatic patients with chronic aortic regurgitation and normal left ventricular performance. Borer, J.S., Hochreiter, C., Herrold, E.M., Supino, P., Aschermann, M., Wencker, D., Devereux, R.B., Roman, M.J., Szulc, M., Kligfield, P., Isom, O.W. Circulation (1998) [Pubmed]
  10. Importance of internal controls, statistical methods, and side effects in short-term trials of vasodilators: a study of hydralazine kinetics in patients with aortic regurgitation. McKay, C.R., Nana, M., Kawanishi, D.T., Elkayam, U., Chandraratna, P.A., Weiss, J.N., Rahimtoola, S.H. Circulation (1985) [Pubmed]
  11. Hemodynamic consequences of afterload reduction in patients with chronic aortic regurgitation. Bolen, J.L., Alderman, E.L. Circulation (1976) [Pubmed]
  12. Echocardiographic evaluation of the response to afterload stress test in young asymptomatic patients with chronic severe aortic regurgitation: sensitivity of the left ventricular end-systolic pressure-volume relationship. Branzi, A., Lolli, C., Piovaccari, G., Rapezzi, C., Binetti, G., Specchia, S., Zannoli, R., Magnani, B. Circulation (1984) [Pubmed]
  13. Assessment of left ventricular mechanics in patients with asymptomatic aortic regurgitation: a two-dimensional echocardiographic study. St John Sutton, M.G., Plappert, T.A., Hirshfeld, J.W., Reichek, N. Circulation (1984) [Pubmed]
  14. Observations on the optimum time for operative intervention for aortic regurgitation. II. Serial echocardiographic evaluation of asymptomatic patients. Henry, W.L., Bonow, R.O., Rosing, D.R., Epstein, S.E. Circulation (1980) [Pubmed]
  15. Comparison between apexcardiographic and angiographic indexes of left ventricular performance in patients with aortic incompetence. Manolas, J., Krayenbuehl, H.P. Circulation (1978) [Pubmed]
  16. Noninvasive assessment of load reduction in patients with asymptomatic aortic regurgitation. Wilson, J.R., Reichek, N., Hirshfeld, J. Am. J. Med. (1980) [Pubmed]
  17. Use of the left ventricular peak systolic pressure/end-systolic volume ratio to predict symptomatic improvement with valve replacement in patients with aortic regurgitation and enlarged end-systolic volume. Pirwitz, M.J., Lange, R.A., Willard, J.E., Landau, C., Glamann, D.B., Hillis, L.D. J. Am. Coll. Cardiol. (1994) [Pubmed]
  18. Haemodynamic effects of arterial compliance, total peripheral resistance, and glyceryl trinitrate on regurgitant volume in aortic regurgitation. Slørdahl, S.A., Piene, H. Cardiovasc. Res. (1991) [Pubmed]
  19. Vasodilatation with felodipine in chronic asymptomatic aortic regurgitation. Søndergaard, L., Aldershvile, J., Hildebrandt, P., Kelbaek, H., Ståhlberg, F., Thomsen, C. Am. Heart J. (2000) [Pubmed]
  20. Effects of perindopril on left ventricular remodeling and aortic regurgitation in rats assessed by echocardiography. Murakami, K., Mizushige, K., Noma, T., Kimura, S., Abe, Y., Matsuo, H. Angiology. (2000) [Pubmed]
  21. Echographic early systolic partial closure (notching) of the aortic valve in congestive cardiomyopathy. Gardin, J.M., Tommaso, C.L., Talano, J.V. Am. Heart J. (1984) [Pubmed]
  22. Bundle branch reentrant ventricular tachycardia: cumulative experience in 48 patients. Blanck, Z., Dhala, A., Deshpande, S., Sra, J., Jazayeri, M., Akhtar, M. J. Cardiovasc. Electrophysiol. (1993) [Pubmed]
  23. Two-dimensional echocardiography and color Doppler imaging in patients with systolic-diastolic murmurs. Vargas-Barron, J., Attie, F., Skronme, D., Sanchez-Ugarte, T., Keirns, C., Santana-Gonzalez, A. Am. Heart J. (1987) [Pubmed]
  24. Acute aortitis and aortic incompetence due to systemic rheumatological disorders. Townend, J.N., Emery, P., Davies, M.K., Littler, W.A. International journal of cardiology. (1991) [Pubmed]
  25. Dexfenfluramine and heart-valve regurgitation in Chinese patients with type 2 diabetes. Ko, G.T., Chan, H.C., Chow, C.C. Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine. (2003) [Pubmed]
  26. The effect of valvular regurgitation on plasma Cardiotrophin-1 in patients with normal left ventricular systolic function. Talwar, S., Squire, I.B., Davies, J.E., Ng, L.L. Eur. J. Heart Fail. (2000) [Pubmed]
  27. Ventricular septal defect with aortic regurgitation. Keane, J.F., Plauth, W.H., Nadas, A.S. Circulation (1977) [Pubmed]
  28. Absence of pulsus paradoxus in a patient with cardiac tamponade and coexisting pulmonary artery obstruction. Cunningham, M.J., Safian, R.D., Come, P.C., Lorell, B.H. Am. J. Med. (1987) [Pubmed]
  29. Aortic valve incompetence and replacement in rheumatoid arthritis. Iveson, J.M., Thadani, U., Ionescu, M., Wright, V. Ann. Rheum. Dis. (1975) [Pubmed]
  30. Aortic incompetence in HLA B27-positive juvenile arthritis. Kean, W.F., Anastassiades, T.P., Ford, P.M. Ann. Rheum. Dis. (1980) [Pubmed]
  31. Pulmonary atresia with ventricular septal defect and aortic regurgitation: diagnosis by echocardiography with diastolic vibration of both right and left sides of the ventricular septum. DePace, N., Kotler, M.N., Mintz, G.S., Bemis, C.E., Glazier-Laskey, E.E. Am. J. Cardiol. (1983) [Pubmed]
  32. Afterload reduction therapy with nitroprusside in severe aortic regurgitation: improved cardiac performance and reduced regurgitant volume. Miller, R.R., Vismara, L.A., DeMaria, A.N., Salel, A.F., Mason, D.T. Am. J. Cardiol. (1976) [Pubmed]
  33. Reoperation after aortic valvuloplasty for aortic regurgitation associated with ventricular septal defect. Ohkita, Y., Miki, S., Kusuhara, K., Ueda, Y., Tahata, T., Komeda, M., Tamura, T. Ann. Thorac. Surg. (1986) [Pubmed]
  34. Assessment of hemodynamic effects of angiotensin-converting enzyme inhibitor therapy in chronic aortic regurgitation by using velocity-encoded cine magnetic resonance imaging. Globits, S., Blake, L., Bourne, M., Fujita, N., Duerinckx, A., Szolar, D., Cheitlin, M., Higgins, C.B. Am. Heart J. (1996) [Pubmed]
  35. Congenital bicuspid aortic valve enodocarditis with multiple subvalvular complications and an acquired membranous ventricular septal defect. Zelenka, J., Akel, R., Sawada, S.G., Mahenthiran, J. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography. (2003) [Pubmed]
WikiGenes - Universities