The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Metabolism of perorally administered xylitol in rat tissues.

Rats were given xylitol (X) or glucose ( G) in drinking water for a period of 28-33 days of which the last 2 days also comprised intake of 14C(U)-X or -G. Samples of plasma, liver, kidneys, pancreas, duodenum and the parotid, submandibular and lacrimal glands were homogenized and separated into various fractions for radioactivity and chemical analyses. The X-fed animals had smaller lacrimal and submandibular glands than the G-fed siblings. The radioactivities of the plasma, liver and kidney trichloroacetic acid extracts of both sexes increased more in the X-groups. X increased the incorporation of the label into the total lipids of plasma, liver and duodenum in both sexes. In males, X increased the labeling of both the neutral lipids and phospholipids. In females, X increased plasma lysolecithin and decreased plasma lecithin. The organs of the X-fed females contained less ascorbic acid than those of the G-fed animals, except for plasma and the parotid glands. Several organs of the males also showed this phenomenon. X and G thus exerted selective effects on the exocrine glands. Although X entered easily the regular G metabolism and acted as a physiological carbon source, the incorporation of labeled X was, however, sex-dependent. The relationship between peroral xylitol and the metabolism of phospholipids and ascorbic acid should be especially considered in rats.[1]

References

  1. Metabolism of perorally administered xylitol in rat tissues. Hämäläinen, M.M., Mäkinen, K.K. J. Nutr. (1981) [Pubmed]
 
WikiGenes - Universities