- Production of interleukin-8 (IL-8) by cultured endothelial cells in response to Borrelia burgdorferi occurs independently of secreted [corrected] IL-1 and tumor necrosis factor alpha and is required for subsequent transendothelial migration of neutrophils. Burns, M.J., Sellati, T.J., Teng, E.I., Furie, M.B. Infect. Immun. (1997)