The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

About

Terms

 

 
 
 
 

Aerobic and anaerobic regulation of the ubiCA operon, encoding enzymes for the first two committed steps of ubiquinone biosynthesis in Escherichia coli.

The ubiCA operon of Escherichia coli encodes enzymes for the first two steps of ubiquinone biosynthesis. A monolysogen (ubiC-lacZ operon fusion) was constructed to study ubiCA regulation. Expression was higher during aerobic growth than anaerobically, and increased with rate of oxygen supply. Although ubiquinone is implicated in antioxidant roles, ubiC expression was not elevated in response to hydrogen peroxide or the redox cycling agent, paraquat. Glucose repressed expression and mutation of cya (encoding adenylate cyclase) increased expression. Anaerobically utilised electron acceptors (nitrite, nitrate, fumarate) did not affect expression. ubiC expression appears to be negatively regulated by Fnr and IHF.[1]

References

  1. Aerobic and anaerobic regulation of the ubiCA operon, encoding enzymes for the first two committed steps of ubiquinone biosynthesis in Escherichia coli. Søballe, B., Poole, R.K. FEBS Lett. (1997) [Pubmed]
Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities