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Chemical Compound Review:

Melitose (3R,4S,5S,6R)-2- [(2S,3S,4S,5R)-3,4...

Synonyms: Melitriose, D-Raffinose, SureCN33744, HMDB03213, LS-71522, ...

Khajavi, S.H. et al., Mooi, F.R. et al., de Lopez, A.G. et al., Pampfer, S. et al.

Pampfer, Vanderheyden, De Hertogh,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Gossypose

The K88 antigen, a plasmid-specified virulence factor of E. coli involved in porcine neonatal diarrhoea, is often found to be associated with the ability to metabolize raffinose (Raf) [1].

High impact information on Gossypose

TNF-alpha secretion was increased in high D-glucose but not in iso-osmolar concentrations of L-glucose, D-raffinose, D-galactose, or mannitol [2].
Plasmid pRI8801 (51 megadalton) was used to clone the determinants of K88 and Raf with the vector pBR322 [1].
The hydrolysis kinetics of trisaccharides consisting of glucose, galactose, and fructose residues with different glycosidic bonds, 1-kestose, d-melezitose, d-raffinose, and lactosucrose, in subcritical water were conducted over the temperature range of 150-230 degrees C and at a constant pressure of 10 MPa [3].
Transfer of drug resistance and enterotoxin production in porcine Escherichia coli strains and relationship between K88 antigen and raffinose (melitose) fermentation [4].

References

Cloning, mapping and expression of the genetic determinant that encodes for the K88ab antigen. Mooi, F.R., de Graaf, F.K., van Embden, J.D. Nucleic Acids Res. (1979) [Pubmed]
Increased synthesis of tumor necrosis factor-alpha in uterine explants from pregnant diabetic rats and in primary cultures of uterine cells in high glucose. Pampfer, S., Vanderheyden, I., De Hertogh, R. Diabetes (1997) [Pubmed]
Hydrolysis kinetics of trisaccharides consisting of glucose, galactose, and fructose residues in subcritical water. Khajavi, S.H., Ota, S., Nakazawa, R., Kimura, Y., Adachi, S. Biotechnol. Prog. (2006) [Pubmed]
Transfer of drug resistance and enterotoxin production in porcine Escherichia coli strains and relationship between K88 antigen and raffinose (melitose) fermentation. de Lopez, A.G., Kadis, S., Shotts, E.B. Am. J. Vet. Res. (1982) [Pubmed]

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