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Chemical Compound Review

CHEBI:28832     (2S,3S,4S,5R,6R)-6- [[(3R,5S,8R,9S,10S,13S...

Synonyms: HMDB02829, KST-1A0068, LMST05010013, AR-1A4744, NSC 113101, ...
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Disease relevance of Androsterone glucuronide


High impact information on Androsterone glucuronide


Chemical compound and disease context of Androsterone glucuronide


Gene context of Androsterone glucuronide


Analytical, diagnostic and therapeutic context of Androsterone glucuronide

  • To investigate the significance of serum androsterone glucuronide, we developed a direct radioimmunoassay for this compound and measured its levels in normal women, women with mild or severe idiopathic hirsutism (IH), hirsute women with polycystic ovarian syndrome (PCO), and non-hirsute obese women [4].


  1. Comparative rates of androgen production and metabolism in Caucasian and Chinese subjects. Santner, S.J., Albertson, B., Zhang, G.Y., Zhang, G.H., Santulli, M., Wang, C., Demers, L.M., Shackleton, C., Santen, R.J. J. Clin. Endocrinol. Metab. (1998) [Pubmed]
  2. Origin and significance of plasma androsterone glucuronide levels: a parameter of adrenal androgen secretion and hepatic 5 alpha-reductase activity. Giagulli, V.A., Giorgino, R., Vermeulen, A. J. Clin. Endocrinol. Metab. (1993) [Pubmed]
  3. Glucosiduronidation and esterification of androsterone by human breast tumors in vitro. Raju, U., Kadner, S., Levitz, M., Kaganowicz, A., Blaustein, A. Steroids (1981) [Pubmed]
  4. Androsterone glucuronide is a marker of adrenal hyperandrogenism in hirsute women. Thompson, D.L., Horton, N., Rittmaster, R.S. Clin. Endocrinol. (Oxf) (1990) [Pubmed]
  5. SHBG Gene Promoter Polymorphisms in Men Are Associated with Serum Sex Hormone-Binding Globulin, Androgen and Androgen Metabolite Levels, and Hip Bone Mineral Density. Eriksson, A.L., Lorentzon, M., Mellstr??m, D., Vandenput, L., Swanson, C., Andersson, N., Hammond, G.L., Jakobsson, J., Rane, A., Orwoll, E.S., Ljunggren, O., Johnell, O., Labrie, F., Windahl, S.H., Ohlsson, C. J. Clin. Endocrinol. Metab. (2006) [Pubmed]
  6. Plasma lipoprotein profile in the male cynomolgus monkey under normal, hypogonadal, and combined androgen blockade conditions. Leblanc, M., Bélanger, M.C., Julien, P., Tchernof, A., Labrie, C., Bélanger, A., Labrie, F. J. Clin. Endocrinol. Metab. (2004) [Pubmed]
  7. The androgen-conjugating uridine diphosphoglucuronosyltransferase-2B enzymes are differentially expressed temporally and spatially in the monkey follicle throughout the menstrual cycle. Barbier, O., Girard, C., Berger, L., El Alfy, M., Bélanger, A., Hum, D.W. Endocrinology (2001) [Pubmed]
  8. Oral testosterone administration detected by testosterone glucuronidation measured in blood spots dried on filter paper. Peng, S.H., Segura, J., Farré, M., de la Torre, X. Clin. Chem. (2000) [Pubmed]
  9. A simple, differential extraction method for the simultaneous direct radioimmunoassay of androgens and androgen glucuronides in human serum. Brind, J., Borofsky, N., Chervinsky, K., Vogelman, J.H., Orentreich, N. Steroids (1996) [Pubmed]
  10. Lifestyle determinants of 5alpha-reductase metabolites in older African-American, white, and Asian-American men. Wu, A.H., Whittemore, A.S., Kolonel, L.N., Stanczyk, F.Z., John, E.M., Gallagher, R.P., West, D.W. Cancer Epidemiol. Biomarkers Prev. (2001) [Pubmed]
  11. Glucosiduronidation of androsterone by human breast tumors in vitro in relation to the progesterone receptor content. Raju, U., Levitz, M., Kaganowicz, A., Blaustein, A. Steroids (1983) [Pubmed]
  12. Differences in clinical and endocrine features between obese and non-obese subjects with polycystic ovary syndrome: an analysis of 263 consecutive cases. Kiddy, D.S., Sharp, P.S., White, D.M., Scanlon, M.F., Mason, H.D., Bray, C.S., Polson, D.W., Reed, M.J., Franks, S. Clin. Endocrinol. (Oxf) (1990) [Pubmed]
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