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Chemical Compound Review

Anaprotin     17-hydroxy-10,13-dimethyl- 1,2,4,5,6,7,8,9...

Synonyms: AGN-PC-00HN7A, SureCN9340073, NSC-15460, NSC-61692, Oprea1_456186, ...
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Disease relevance of dihydrotestosterone


Psychiatry related information on dihydrotestosterone


High impact information on dihydrotestosterone


Chemical compound and disease context of dihydrotestosterone


Biological context of dihydrotestosterone


Anatomical context of dihydrotestosterone


Associations of dihydrotestosterone with other chemical compounds


Gene context of dihydrotestosterone


Analytical, diagnostic and therapeutic context of dihydrotestosterone

  • More importantly, both DDPCR and Northern blot analysis further demonstrated that the expression of TDD5 was differentially repressed by T and dihydrotestosterone (DHT) at the mRNA level [37].
  • Furthermore, after post-castration regression of the prostate for 3 days, three daily subcutaneous injections of dihydrotestosterone resulted in a complete restoration of type I activity toe the intact level [38].
  • In other experiments it has been found that the gene expression of Po may be decreased by orchidectomy and restored by treatment with the androgen dihydrotestosterone [39].
  • In contrast, although oophorectomy did not significantly influence rAAV transduction, administration of 5alpha dihydrotestosterone, prior to gene transfer, increased stable hepatocyte gene transfer in females to levels observed in male mice, implying that androgens significantly influence hepatocyte gene transfer [40].
  • Surprisingly, one of the inhibitors of 17alpha-hydroxylase/C17,20-lyase, 17beta-(4-imidazolyl)-5-pregnen-3beta-ol, was also able to inhibit the mitogenic effect of testosterone in both the histoculture and cell culture assays and had an effect against DHT as well [41].


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