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MeSH Review

Addison Disease

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Disease relevance of Addison Disease


High impact information on Addison Disease


Chemical compound and disease context of Addison Disease


Biological context of Addison Disease


Anatomical context of Addison Disease


Gene context of Addison Disease


Analytical, diagnostic and therapeutic context of Addison Disease


  1. Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters. Mosser, J., Douar, A.M., Sarde, C.O., Kioschis, P., Feil, R., Moser, H., Poustka, A.M., Mandel, J.L., Aubourg, P. Nature (1993) [Pubmed]
  2. Premature ovarian failure and ovarian autoimmunity. Hoek, A., Schoemaker, J., Drexhage, H.A. Endocr. Rev. (1997) [Pubmed]
  3. A conformation-dependent epitope in Addison's disease and other endocrinological autoimmune diseases maps to a carboxyl-terminal functional domain of human steroid 21-hydroxylase. Nikoshkov, A., Falorni, A., Lajic, S., Laureti, S., Wedell, A., Lernmark, K., Luthman, H. J. Immunol. (1999) [Pubmed]
  4. Azidothymidine-induced hyperpigmentation mimicking primary adrenal insufficiency. Merenich, J.A., Hannon, R.N., Gentry, R.H., Harrison, S.M. Am. J. Med. (1989) [Pubmed]
  5. Primary empty sella syndrome, ACTH hypersecretion, and normal adrenocortical function. Report of two cases. Sindler, B.H., Griffing, G.T., Melby, J.C. Am. J. Med. (1982) [Pubmed]
  6. Urine free-cortisol determination. A useful tool in the management of chronic hypoadrenal states. Burch, W.M. JAMA (1982) [Pubmed]
  7. Acute Addison's disease and heparin. Ahmad, S. JAMA (1979) [Pubmed]
  8. A novel mutation in DAX1 causes delayed-onset adrenal insufficiency and incomplete hypogonadotropic hypogonadism. Tabarin, A., Achermann, J.C., Recan, D., Bex, V., Bertagna, X., Christin-Maitre, S., Ito, M., Jameson, J.L., Bouchard, P. J. Clin. Invest. (2000) [Pubmed]
  9. Two different cytochrome P450 enzymes are the adrenal antigens in autoimmune polyendocrine syndrome type I and Addison's disease. Winqvist, O., Gustafsson, J., Rorsman, F., Karlsson, F.A., Kämpe, O. J. Clin. Invest. (1993) [Pubmed]
  10. Secondary pituitary hyperplasia in Addison's disease. Clayton, R., Burden, A.C., Schrieber, V., Rosenthal, F.D. Lancet (1977) [Pubmed]
  11. Subclinical Addison's disease: a cause of persistent abnormalities in transaminase values. Boulton, R., Hamilton, M.I., Dhillon, A.P., Kinloch, J.D., Burroughs, A.K. Gastroenterology (1995) [Pubmed]
  12. Evidence that patients with Addison's disease are undertreated with fludrocortisone. Smith, S.J., MacGregor, G.A., Markandu, N.D., Bayliss, J., Banks, R.A., Prentice, M.G., Dorrington-Ward, P., Wise, P. Lancet (1984) [Pubmed]
  13. Improvement in mood and fatigue after dehydroepiandrosterone replacement in Addison's disease in a randomized, double blind trial. Hunt, P.J., Gurnell, E.M., Huppert, F.A., Richards, C., Prevost, A.T., Wass, J.A., Herbert, J., Chatterjee, V.K. J. Clin. Endocrinol. Metab. (2000) [Pubmed]
  14. Microsatellite polymorphism of the MHC class I chain-related (MIC-A and MIC-B) genes marks the risk for autoimmune Addison's disease. Gambelunghe, G., Falorni, A., Ghaderi, M., Laureti, S., Tortoioli, C., Santeusanio, F., Brunetti, P., Sanjeevi, C.B. J. Clin. Endocrinol. Metab. (1999) [Pubmed]
  15. AIRE mutations and human leukocyte antigen genotypes as determinants of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy phenotype. Halonen, M., Eskelin, P., Myhre, A.G., Perheentupa, J., Husebye, E.S., Kämpe, O., Rorsman, F., Peltonen, L., Ulmanen, I., Partanen, J. J. Clin. Endocrinol. Metab. (2002) [Pubmed]
  16. Hormonal changes in puberty III: Correlation of plasma dehydroepiandrosterone, testosterone, FSH, and LH with stages of puberty and bone age in normal boys and girls and in patients with Addison's disease or hypogonadism or with premature or late adrenarche. Sizonenko, P.C., Paunier, L. J. Clin. Endocrinol. Metab. (1975) [Pubmed]
  17. Human plasma proopiomelanocortin N-terminal peptide and adrenocorticotropin: circadian rhythm, dexamethasone suppression, and corticotropin-releasing hormone stimulation. Motomatsu, T., Takahashi, H., Ibayashi, H., Nobunaga, M. J. Clin. Endocrinol. Metab. (1984) [Pubmed]
  18. 21-Hydroxylase, a major autoantigen in idiopathic Addison's disease. Winqvist, O., Karlsson, F.A., Kämpe, O. Lancet (1992) [Pubmed]
  19. Clinical review: Type 1 diabetes-associated autoimmunity: natural history, genetic associations, and screening. Barker, J.M. J. Clin. Endocrinol. Metab. (2006) [Pubmed]
  20. Thyroid-stimulating antibodies in patients with autoimmune disorders. Strakosch, C.R., Joyner, D., Wall, J.R. J. Clin. Endocrinol. Metab. (1978) [Pubmed]
  21. Inherited susceptibility to autoimmune Addison's disease is linked to human leukocyte antigens-DR3 and/or DR4, except when associated with type I autoimmune polyglandular syndrome. Maclaren, N.K., Riley, W.J. J. Clin. Endocrinol. Metab. (1986) [Pubmed]
  22. Acutely raised corticotropin levels in Addison's disease are not associated with increased plasma arginine vasopressin and corticotropin-releasing factor concentrations in peripheral plasma. Wittert, G.A., Livesey, J.H., Florkowski, C., Or, H.K., Donald, R.A., Espiner, E.A. J. Clin. Endocrinol. Metab. (1993) [Pubmed]
  23. Elevated serum interferon-gamma-inducible chemokine-10/CXC chemokine ligand-10 in autoimmune primary adrenal insufficiency and in vitro expression in human adrenal cells primary cultures after stimulation with proinflammatory cytokines. Rotondi, M., Falorni, A., De Bellis, A., Laureti, S., Ferruzzi, P., Romagnani, P., Buonamano, A., Lazzeri, E., Crescioli, C., Mannelli, M., Santeusanio, F., Bellastella, A., Serio, M. J. Clin. Endocrinol. Metab. (2005) [Pubmed]
  24. Autoantibodies against CYP2D6 and other drug-metabolizing enzymes in autoimmune hepatitis type 2. Mizutani, T., Shinoda, M., Tanaka, Y., Kuno, T., Hattori, A., Usui, T., Kuno, N., Osaka, T. Drug Metab. Rev. (2005) [Pubmed]
  25. Androgen production in women. Burger, H.G. Fertil. Steril. (2002) [Pubmed]
  26. Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiency. Skinningsrud, B., Husebye, E.S., Pearce, S.H., McDonald, D.O., Brandal, K., Wolff, A.B., Løvås, K., Egeland, T., Undlien, D.E. J. Clin. Endocrinol. Metab. (2008) [Pubmed]
  27. Identification by molecular cloning of an autoantigen associated with Addison's disease as steroid 17 alpha-hydroxylase. Krohn, K., Uibo, R., Aavik, E., Peterson, P., Savilahti, K. Lancet (1992) [Pubmed]
  28. Adrenal-cortex autoantibodies and steroid-producing cells autoantibodies in patients with Addison's disease: comparison of immunofluorescence and immunoprecipitation assays. Betterle, C., Volpato, M., Pedini, B., Chen, S., Smith, B.R., Furmaniak, J. J. Clin. Endocrinol. Metab. (1999) [Pubmed]
  29. Effects of a met-enkephalin analog on adrenocorticotropin (ACTH), growth hormone, and prolactin in patients with ACTH hypersecretion. Allolio, B., Winkelmann, W., Hipp, F.X., Kaulen, D., Mies, R. J. Clin. Endocrinol. Metab. (1982) [Pubmed]
  30. Androgen therapy in women. Arlt, W. Eur. J. Endocrinol. (2006) [Pubmed]
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