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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

Glycolanilide     N-(2-hydroxyphenyl)ethanamide

Synonyms: PubChem3830, SureCN79487, A7000_ALDRICH, ARONIS023702, NSC-3989, ...
 
 
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Disease relevance of O-ACETYLAMINOPHENOL

  • The relative order of potency of isomers in stimulating proliferation in both cell types was p- > m- > o-acetamidophenol, indicating the -OH position on the benzene ring influences the proliferation output in cultured breast cancer cells [1].
  • Isolation, identification, and accumulation of 2-acetamidophenol in liquid cultures of the wheat take-all biocontrol agent Pseudomonas fluorescens 2-79 [2].
 

High impact information on O-ACETYLAMINOPHENOL

 

Biological context of O-ACETYLAMINOPHENOL

  • The biotransformation of the phytoanticipin HBOA and its major degradation metabolites 2-hydroxy-N-(2-hydroxyphenyl)acetamide (7) and N-(2-hydroxyphenyl)acetamide (8) by Chaetosphaeria sp., an endophytic fungus isolated from Aphelandra tetragona, was studied [7].
 

Analytical, diagnostic and therapeutic context of O-ACETYLAMINOPHENOL

References

  1. Positional isomers of acetaminophen differentially induce proliferation of cultured breast cancer cells. Harnagea-Theophilus, E., Miller, M.R., Rao, N. Toxicol. Lett. (1999) [Pubmed]
  2. Isolation, identification, and accumulation of 2-acetamidophenol in liquid cultures of the wheat take-all biocontrol agent Pseudomonas fluorescens 2-79. Slininger, P.J., Burkhead, K.D., Schisler, D.A., Bothast, R.J. Appl. Microbiol. Biotechnol. (2000) [Pubmed]
  3. Biotransformation of 2-benzoxazolinone and 2-hydroxy-1,4-benzoxazin-3-one by endophytic fungi isolated from Aphelandra tetragona. Zikmundová, M., Drandarov, K., Bigler, L., Hesse, M., Werner, C. Appl. Environ. Microbiol. (2002) [Pubmed]
  4. The metabolism of 2- and 3-hydroxyacetanilide. Determination of metabolic products by liquid chromatography/electrochemistry. Hamilton, M., Kissinger, P.T. Drug Metab. Dispos. (1986) [Pubmed]
  5. Zea mays: benzoxazolinone detoxification under sulfur deficiency conditions-a complex allelopathic alliance including endophytic fusarium verticillioides. Knop, M., Pacyna, S., Voloshchuk, N., Kant, S., Müllenborn, C., Steiner, U., Kirchmair, M., Scherer, H.W., Schulz, M. J. Chem. Ecol. (2007) [Pubmed]
  6. Detection and identification of three thioether conjugates of 2-hydroxyacetanilide by liquid chromatography/electrochemistry. Rottero, A.E., Kissinger, P. Biomed. Chromatogr. (1987) [Pubmed]
  7. Hydroxylated 2-amino-3H-phenoxazin-3-one derivatives as products of 2-hydroxy-1,4-benzoxazin-3-one (HBOA) biotransformation by Chaetosphaeria sp., an endophytic fungus from Aphelandra tetragona. Zikmundová, M., Drandarov, K., Hesse, M., Werner, C. Z. Naturforsch., C, J. Biosci. (2002) [Pubmed]
 
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