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Chemical Compound Review

Benzoxazolone     3H-benzooxazol-2-one

Synonyms: PubChem8633, SureCN19555, CHEMBL280323, SureCN140087, Bio-0268, ...
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High impact information on NSC3812


Biological context of NSC3812


Anatomical context of NSC3812

  • Therefore, in the present study, the effects of six of the above mentioned benzoxazolone and benzothiazolone derivatives bearing 2-pyridylaminocarbonylmetyl moiety at the position 3 (I) on the antioxidant system-related parameters of human erythrocytes have been investigated [7].

Associations of NSC3812 with other chemical compounds


Analytical, diagnostic and therapeutic context of NSC3812

  • Analytical HPLC methods using derivatized cellulose chiral stationary phases were developed for the direct enantioseparation of substituted [1-(imidazo-1-yl)-1-phenylmethyl)]-benzothiazolinone and benzoxazolinone derivatives with one chiral center [10].
  • Identification of several human urinary metabolites of 6-benzoyl benzoxazolinone by gas chromatography/mass spectrometry [11].


  1. Identification of intermediate and branch metabolites resulting from biotransformation of 2-benzoxazolinone by Fusarium verticillioides. Glenn, A.E., Meredith, F.I., Morrison, W.H., Bacon, C.W. Appl. Environ. Microbiol. (2003) [Pubmed]
  2. Zea mays: benzoxazolinone detoxification under sulfur deficiency conditions-a complex allelopathic alliance including endophytic fusarium verticillioides. Knop, M., Pacyna, S., Voloshchuk, N., Kant, S., Müllenborn, C., Steiner, U., Kirchmair, M., Scherer, H.W., Schulz, M. J. Chem. Ecol. (2007) [Pubmed]
  3. 2-Benzoxazolinone (BOA) induced oxidative stress, lipid peroxidation and changes in some antioxidant enzyme activities in mung bean (Phaseolus aureus). Batish, D.R., Singh, H.P., Setia, N., Kaur, S., Kohli, R.K. Plant Physiol. Biochem. (2006) [Pubmed]
  4. Synthesis of some 2(3H)-benzoxazolone derivatives and their in-vitro effects on human leukocyte myeloperoxidase activity. Soyer, Z., Bas, M., Pabuccuoglu, A., Pabuccuoglu, V. Arch. Pharm. (Weinheim) (2005) [Pubmed]
  5. Biotransformation of 2-benzoxazolinone and 2-hydroxy-1,4-benzoxazin-3-one by endophytic fungi isolated from Aphelandra tetragona. Zikmundová, M., Drandarov, K., Bigler, L., Hesse, M., Werner, C. Appl. Environ. Microbiol. (2002) [Pubmed]
  6. Nitrosation of benzoxazolinone. Baker, J.K. Bulletin of environmental contamination and toxicology. (1976) [Pubmed]
  7. The in vitro effects of new non-steroidal antiinflammatory compounds on antioxidant system of human erythrocytes. Orhan, H., Doğruer, D.S., Cakir, B., Sahin, G., Sahin, M.F. Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie. (1999) [Pubmed]
  8. Synthesis and in vitro activity of new cephem derivatives with benzoxazolone ring. Mincheva, Z.P., Kalcheva, V.B., Golovinsky, E.G., Tabakova, S.V. Die Pharmazie. (1993) [Pubmed]
  9. Synthesis and in vitro activity of new cephalosporin derivatives containing a benzoxazolone ring. Kalcheva, V., Mincheva, Z., Andreeva, P. Arzneimittel-Forschung. (1990) [Pubmed]
  10. Enantiomeric resolution of new aromatase inhibitors by liquid chromatography on cellulose chiral stationary phases. Danel, C., Foulon, C., Park, C., Yous, S., Bonte, J.P., Vaccher, C. Journal of separation science. (2005) [Pubmed]
  11. Identification of several human urinary metabolites of 6-benzoyl benzoxazolinone by gas chromatography/mass spectrometry. Bastide, M., Chabard, J.L., Lartigue, C., Bargnoux, H., Petit, J., Berger, J.A., Mansour, H.A., Lesieur, D., Buch, N. Biol. Mass Spectrom. (1991) [Pubmed]
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