Chemical Compound Review:
Repinotan 8-[4-[[(2R)-chroman-2- yl]methylamino]butyl...
Synonyms:
SureCN678644, CHEMBL1614652, DNC000279, Bay x3702, AC1L55ZL, ...
- Neuroprotective efficacy of repinotan HCl, a 5-HT1A receptor agonist, in animal models of stroke and traumatic brain injury. Mauler, F., Horváth, E. J. Cereb. Blood Flow Metab. (2005)
- The BRAINS study: safety, tolerability, and dose-finding of repinotan in acute stroke. Teal, P., Silver, F.L., Simard, D. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. (2005)
- The selective 5-HT(1A) receptor agonist repinotan HCl attenuates histopathology and spatial learning deficits following traumatic brain injury in rats. Kline, A.E., Yu, J., Horváth, E., Marion, D.W., Dixon, C.E. Neuroscience (2001)
- 5-HT1A receptor agonist-mediated protection from MPTP toxicity in mouse and macaque models of Parkinson's disease. Bezard, E., Gerlach, I., Moratalla, R., Gross, C.E., Jork, R. Neurobiol. Dis. (2006)
- Repinotan (BAY x 3702): a 5HT1A agonist in traumatically brain injured patients. Ohman, J., Braakman, R., Legout, V. J. Neurotrauma (2001)
- A Review of the Neuroprotective Properties of the 5-HT(1A) Receptor Agonist Repinotan HCl (BAY x 3702) in Ischemic Stroke. Berends, A.C., Luiten, P.G., Nyakas, C. CNS drug reviews. (2005)
- Pharmacokinetics of repinotan in healthy and brain injured animals. Schwarz, T., Beckermann, B., Buehner, K., Mauler, F., Schuhmacher, J., Seidel, D., Steinke, W., Weinz, C., Zimmerd, D. Biopharmaceutics & drug disposition. (2005)
- Repinotan, A 5-HT1A agonist, in the treatment of acute ischemic stroke. Lutsep, H.L. Current drug targets. CNS and neurological disorders. (2005)
- Evaluation of interethnic differences in repinotan pharmacokinetics by using population approach. Tanigawa, T., Heinig, R., Kuroki, Y., Higuchi, S. Drug Metab. Pharmacokinet. (2006)