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MeSH Review

Hematoma, Subdural, Acute

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Disease relevance of Hematoma, Subdural, Acute


High impact information on Hematoma, Subdural, Acute


Chemical compound and disease context of Hematoma, Subdural, Acute


Biological context of Hematoma, Subdural, Acute


Gene context of Hematoma, Subdural, Acute

  • We tested the neuroprotective effect of a novel, high affinity serotonin (5-HT1A) agonist, BAY X3702, in a rat model of acute subdural hematoma (ASDH) [11].
  • BACKGROUND: Patients who have an acute subdural hematoma with a thickness of 10 mm or less and with a shift of the midline structures of 5 mm or less often can be treated nonoperatively [14].
  • Treatment of acute subdural hematoma with a low GCS score [15].
  • Follow-up CT scan of brain 2 hours after the initial one showed resolution and redistribution of the subdural hematoma.To our knowledge, this is the first case in the literature about spontaneous resolution of an acute subdural hematoma in a patient with a linear fracture and the fastest resolution period [16].

Analytical, diagnostic and therapeutic context of Hematoma, Subdural, Acute

  • The patient was a fifty two years old man, mechanic valve recipient with Warfarin-induced coagulopathy: International Normalization Ratio (INR) of 6.39, who suffered from acute subdural hematoma and needed urgent neurosurgical intervention [17].


  1. Improving clinical outcomes from acute subdural hematomas with the emergency preoperative administration of high doses of mannitol: a randomized trial. Cruz, J., Minoja, G., Okuchi, K. Neurosurgery (2001) [Pubmed]
  2. Simulation of acute subdural hematoma and diffuse axonal injury in coronal head impact. Bradshaw, D.R., Ivarsson, J., Morfey, C.L., Viano, D.C. Journal of biomechanics. (2001) [Pubmed]
  3. New head-prone position for posterior fossa surgery in infants with severe hydrocephalus. Rayport, M., Martin, J.T. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. (1992) [Pubmed]
  4. Acute subdural hematoma associated with cerebral infarction in the full-term neonate. Steinbok, P., Haw, C.S., Cochrane, D.D., Kestle, J.R. Pediatric neurosurgery. (1995) [Pubmed]
  5. Neuroprotective efficacy of repinotan HCl, a 5-HT1A receptor agonist, in animal models of stroke and traumatic brain injury. Mauler, F., Horváth, E. J. Cereb. Blood Flow Metab. (2005) [Pubmed]
  6. Tempol, a novel stable nitroxide, reduces brain damage and free radical production, after acute subdural hematoma in the rat. Kwon, T.H., Chao, D.L., Malloy, K., Sun, D., Alessandri, B., Bullock, M.R. J. Neurotrauma (2003) [Pubmed]
  7. Reducing hemoglobin oxygen affinity does not increase hydroxyl radicals after acute subdural hematoma in the rat. Doppenberg, E.M., Rice, M.R., Alessandri, B., Qian, Y., Di, X., Bullock, R. J. Neurotrauma (1999) [Pubmed]
  8. The neuroprotective effect of the forebrain-selective NMDA antagonist CP101,606 upon focal ischemic brain damage caused by acute subdural hematoma in the rat. Tsuchida, E., Rice, M., Bullock, R. J. Neurotrauma (1997) [Pubmed]
  9. Neuroprotection by dextromethorphan in acute experimental subdural hematoma in the rat. Duhaime, A.C., Gennarelli, L.M., Boardman, C. J. Neurotrauma (1996) [Pubmed]
  10. Glucose hypermetabolism after acute subdural hematoma is ameliorated by a competitive NMDA antagonist. Inglis, F., Kuroda, Y., Bullock, R. J. Neurotrauma (1992) [Pubmed]
  11. The neuroprotective effect of a new serotonin receptor agonist, BAY X3702, upon focal ischemic brain damage caused by acute subdural hematoma in the rat. Alessandri, B., Tsuchida, E., Bullock, R.M. Brain Res. (1999) [Pubmed]
  12. Acute regional cerebral blood flow changes caused by severe head injuries. Marion, D.W., Darby, J., Yonas, H. J. Neurosurg. (1991) [Pubmed]
  13. Effect of neuroprotective N-methyl-D-aspartate antagonists on increased intracranial pressure: studies in the rat acute subdural hematoma model. Kuroda, Y., Fujisawa, H., Strebel, S., Graham, D.I., Bullock, R. Neurosurgery (1994) [Pubmed]
  14. Importance of a reliable admission Glasgow Coma Scale score for determining the need for evacuation of posttraumatic subdural hematomas: a prospective study of 65 patients. Servadei, F., Nasi, M.T., Cremonini, A.M., Giuliani, G., Cenni, P., Nanni, A. The Journal of trauma. (1998) [Pubmed]
  15. Treatment of acute subdural hematoma with a low GCS score. Shigemori, M., Tokutomi, T., Yamamoto, F., Kobayashi, S., Nakashima, H., Watanabe, M., Kuramoto, S. Neurosurgical review. (1989) [Pubmed]
  16. Ultra rapid spontaneous resolution of acute posttraumatic subdural hematomas in patient with temporal linear fracture. Berker, M., Gulsen, S., Ozcan, O.E. Acta neurochirurgica. (2003) [Pubmed]
  17. Recombinant coagulation factor VIIa for rapid preoperative correction of warfarin-related coagulopathy in patients with acute subdural hematoma. Veshchev, I., Elran, H., Salame, K. Med. Sci. Monit. (2002) [Pubmed]
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