Chemical Compound Review:
CCRIS 339 N-(4-ethoxyphenyl)-N-hydroxy- ethanamide
Synonyms:
NSC-229647, AC1L1HNK, LS-13108, NSC229647, AKOS006272871, ...
- Mechanism of N-hydroxyacetylarylamine mutagenicity in the Salmonella test system: metabolic activation of N-hydroxyphenacetin by liver and kidney fractions from rat, mouse, hamster, and man. Wirth, P.J., Dybing, E., von Bahr, C., Thorgeirsson, S.S. Mol. Pharmacol. (1980)
- N-Hydroxy-N-arylacetamides. I. Toxicity of certain polycyclic and monocyclic N-hydroxy-N-arylacetamides in rats. Fischbach, T., Hertle, H., Kiese, M., Lenk, W., Sterzl, H., Meister, P. Arch. Toxicol. (1984)
- Inhibition of DNA, RNA and protein synthesis and chromatin alteration by N-hydroxyphenacetin. Hayward, N.K., Lavin, M.F. Xenobiotica (1987)
- Metabolic activation and genotoxicity of N-hydroxy-2-acetylaminofluorene and N-hydroxyphenacetin derivatives in Reuber (H4-II-E) hepatoma cells. Glowinski, I.B., Sanderson, N.D., Hayashi, S., Thorgeirsson, S.S. Cancer Res. (1984)
- Species-specific activation of phenacetin into bacterial mutagens by hamster liver enzymes and identification of N-hydroxyphenacetin O-glucuronide as a promutagen in the urine. Camus, A.M., Friesen, M., Croisy, A., Bartsch, H. Cancer Res. (1982)
- Activation of N-hydroxyphenacetin to mutagenic and nucleic acid-binding metabolites by acyltransfer, deacylation, and sulfate conjugation. Vaught, J.B., McGarvey, P.B., Lee, M.S., Garner, C.D., Wang, C.Y., Linsmaier-Bednar, E.M., King, C.M. Cancer Res. (1981)
- N-hydroxyphenacetin, a new urinary metabolite of phenacetin in the rat. McLean, S., Davies, N.W., Watson, H., Favretto, W.A., Bignall, J.C. Drug Metab. Dispos. (1981)
- Metabolism of phenacetin and N-hydroxyphenacetin in isolated rat hepatocytes. McLean, S. Naunyn Schmiedebergs Arch. Pharmacol. (1978)
- N-Hydroxylation of phenacetin by hamster liver microsomes. Hinson, J.A., Mitchell, J.R. Drug Metab. Dispos. (1976)
- The metabolism of N-hydroxyphenacetin in vitro and in vivo. Fischbach, T., Lenk, W. Xenobiotica (1985)
- Mass spectrometric determination of N-hydroxyphenacetin in urine using multiple metastable peak monitoring following thin-layer chromatography. Davies, N.W., Veronese, M.E., McLean, S. J. Chromatogr. (1984)