Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Cholevue 3-[3-[2-[2-[2-[2-[(3-carboxy- 2,4,6-triiodo...

Synonyms: Endomirabil, Iodoxamsaeure, Videocolangio, Iodoxamic acid, BC-17, ...

Berk, R.N. et al., Moss, A.A. et al., Lin, S.K. et al., Lin, S.K. et al., Nakata, H. et al.

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Disease relevance of EINECS 250-478-1

The biliary excretion and choleretic effects of iodoxamate (Cholevue) and iodipamide (Cholografin) were compared in unanesthetized dogs with biliary fistulas in order to assess the potential of the two contrast agents for use in intravenous cholangiography [1].

High impact information on EINECS 250-478-1

Using the Freundlich isotherm approach, more than one class of binding site for iodoxamic acid was found [2].
Less than 1% of iodoxamic acid injected into the duodenum was recovered in the bile in 12 hours [2].
Kinetics of drug-drug interactions: biliary excretion of iodoxamic acid and iopanoic acid in rhesus monkeys [3].
Pharmacokinetics of iodoxamic acid in rhesus monkey: biliary excretion, plasma protein binding, and enterophepatic circulation [4].
Usefulness of iotroxic acid for drip infusion cholegraphy -- comparison with iodoxamic acid preparations [5].

References

Saturation kinetics and choleretic effects of iodoxamate and iodipamide. Berk, R.N., Loeb, P.M., Cobo-Frenkel, A., Barnhart, J.L. Radiology. (1976) [Pubmed]
Gastrointestinal radiology. Pharmacokinetics of iopanoate and iodoxamate in rhesus monkeys. Moss, A.A., Lin, S.K., Riegelman, S. Investigative radiology. (1980) [Pubmed]
Kinetics of drug-drug interactions: biliary excretion of iodoxamic acid and iopanoic acid in rhesus monkeys. Lin, S.K., Moss, A.A., Riegelman, S. Journal of pharmaceutical sciences. (1979) [Pubmed]
Pharmacokinetics of iodoxamic acid in rhesus monkey: biliary excretion, plasma protein binding, and enterophepatic circulation. Lin, S.K., Moss, A.A., Motson, R., Riegelman, S. Journal of pharmaceutical sciences. (1978) [Pubmed]
Usefulness of iotroxic acid for drip infusion cholegraphy -- comparison with iodoxamic acid preparations. Nakata, H., Kimoto, T., Matsuura, K., Nishitani, H., Baba, H., Koga, M., Kiyonari, H., Tanaka, M., Shiosaki, H., Matsuoka, J., Ayabe, Y., Nakagawa, E. The British journal of radiology. (1982) [Pubmed]

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