Disease relevance of D-Erythrose

• D-erythrose supports nitrogenase activity in isolated Anabaena sp. strain 7120 heterocysts [1].
• Biosynthesis of vitamin B-12 in anaerobic bacteria. Experiments with Eubacterium limosum and D-erythrose 14C-labeled in different positions [2].
• 1. The tyrosine-sensitive allosteric first enzyme of the aromatic amino acid biosynthetic pathway, 3-deoxy-D-arabinoheptulosonate 7-phosphate synthetase (7-Phospho-2-keto-3-deoxy-D-arabino-heptonate D-erythrose 4-phosphate-lyase (pyruvate phosphorylating), EC 4.1.2.15) has been purified from a mutant strain of Escherichia coli [3].

High impact information on D-Erythrose

• Kinetics of oxygen exchange at the anomeric carbon atom of D-glucose and D-erythrose using the oxygen-18 isotope effect in carbon-13 nuclear magnetic resonance spectroscopy [4].
• However, typical substrates for ALR such as D,L-glyceraldehyde, D-erythrose, D-glucuronate and p-carboxybenzaldehyde could not protect the enzyme from inactivation [5].
• D-Erythrose was conjugated to bovine serum albumin at pH 8 by reductive amination [6].
• The time course of microspherule growth was examined for the D-erythrose-ammonia reaction that yielded microspherules attached to the glass walls of containers [7].
• NADPH-dependent erythrose reductases (ERs) in erythritol-producing fungi, Trichosporonoides megachiliensis SNG-42, catalyze the reduction of D-erythrose [8].

References