The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

UCB35625     2,7-dichloro-N-[1- (cycloheptylmethyl)-1...

Synonyms: UCB 35625, AC1L9Y93, J113863
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of UCB 35625


High impact information on UCB 35625


Anatomical context of UCB 35625


Associations of UCB 35625 with other chemical compounds


Gene context of UCB 35625

  • Thirty-three point mutants of CCR1 were expressed transiently in L1.2 cells, and the cells were assessed for their capacity to migrate in response to CCL3 in the presence or absence of UCB 35625 [2].


  1. A small molecule antagonist of chemokine receptors CCR1 and CCR3. Potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry. Sabroe, I., Peck, M.J., Van Keulen, B.J., Jorritsma, A., Simmons, G., Clapham, P.R., Williams, T.J., Pease, J.E. J. Biol. Chem. (2000) [Pubmed]
  2. Site-directed mutagenesis of CC chemokine receptor 1 reveals the mechanism of action of UCB 35625, a small molecule chemokine receptor antagonist. de Mendonça, F.L., da Fonseca, P.C., Phillips, R.M., Saldanha, J.W., Williams, T.J., Pease, J.E. J. Biol. Chem. (2005) [Pubmed]
  3. Pharmacological blockade of CCR1 ameliorates murine arthritis and alters cytokine networks in vivo. Amat, M., Benjamim, C.F., Williams, L.M., Prats, N., Terricabras, E., Beleta, J., Kunkel, S.L., Godessart, N. Br. J. Pharmacol. (2006) [Pubmed]
WikiGenes - Universities