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Chemical Compound Review

Robinetin     3,7-dihydroxy-2-(3,4,5...

Synonyms: Norkanugin, AC1NQYWM, CHEMBL170405, CCRIS 7520, AG-A-49068, ...
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High impact information on Robinetin


Biological context of Robinetin

  • For one flavonoid, robinetin, the kinetics of inhibition were studied in more detail and revealed competitive inhibition with respect to calcein, with apparent inhibition constants of 5.0 microM for MRP1 and 8.5 microM for MRP2 [3].

Associations of Robinetin with other chemical compounds


  1. Anti-mutagenesis and anti-promotion by apigenin, robinetin and indole-3-carbinol. Birt, D.F., Walker, B., Tibbels, M.G., Bresnick, E. Carcinogenesis (1986) [Pubmed]
  2. Inhibition of the mutagenicity of bay-region diol-epoxides of polycyclic aromatic hydrocarbons by phenolic plant flavonoids. Huang, M.T., Wood, A.W., Newmark, H.L., Sayer, J.M., Yagi, H., Jerina, D.M., Conney, A.H. Carcinogenesis (1983) [Pubmed]
  3. Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2. van Zanden, J.J., Wortelboer, H.M., Bijlsma, S., Punt, A., Usta, M., Bladeren, P.J., Rietjens, I.M., Cnubben, N.H. Biochem. Pharmacol. (2005) [Pubmed]
  4. An in vitro and in silico study on the flavonoid-mediated modulation of the transport of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) through Caco-2 monolayers. Schutte, M.E., Freidig, A.P., van de Sandt, J.J., Alink, G.M., Rietjens, I.M., Groten, J.P. Toxicol. Appl. Pharmacol. (2006) [Pubmed]
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