The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

AC1O3FKV     (2E,6E,8Z)-10-[3-butyl-2- [(E)-4-carboxy-3...

Synonyms: NSC648386
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of AIDS-139358


High impact information on AIDS-139358


Biological context of AIDS-139358

  • Reveromycin A (Rev.A) is an inhibitor of epidermal growth factor-dependent cell growth that is produced from the culture broth of an actinomycete strain [3].

Gene context of AIDS-139358


  1. Reveromycin A, an agent for osteoporosis, inhibits bone resorption by inducing apoptosis specifically in osteoclasts. Woo, J.T., Kawatani, M., Kato, M., Shinki, T., Yonezawa, T., Kanoh, N., Nakagawa, H., Takami, M., Lee, K.H., Stern, P.H., Nagai, K., Osada, H. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
  2. Reveromycin A inhibits osteolytic bone metastasis of small-cell lung cancer cells, SBC-5, through an antiosteoclastic activity. Muguruma, H., Yano, S., Kakiuchi, S., Uehara, H., Kawatani, M., Osada, H., Sone, S. Clin. Cancer Res. (2005) [Pubmed]
  3. Reveromycin A inhibits antigen receptor-mediated antigen presentation by B lymphoma cells via its effect on intracellular trafficking of the antigen. Tanaka, Y., Ishikawa, F., Osada, H., Imajoh-Ohmi, S., Uchida, T., Kakiuchi, T. J. Antibiot. (2002) [Pubmed]
  4. Identification of Saccharomyces cerevisiae isoleucyl-tRNA synthetase as a target of the G1-specific inhibitor Reveromycin A. Miyamoto, Y., Machida, K., Mizunuma, M., Emoto, Y., Sato, N., Miyahara, K., Hirata, D., Usui, T., Takahashi, H., Osada, H., Miyakawa, T. J. Biol. Chem. (2002) [Pubmed]
  5. Total synthesis of reveromycin A. Shimizu, T., Masuda, T., Hiramoto, K., Nakata, T. Org. Lett. (2000) [Pubmed]
  6. Inhibitory action of reveromycin A on TGF-alpha-dependent growth of ovarian carcinoma BG-1 in vitro and in vivo. Takahashi, H., Yamashita, Y., Takaoka, H., Nakamura, J., Yoshihama, M., Osada, H. Oncol. Res. (1997) [Pubmed]
WikiGenes - Universities