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Gene Review

ileS  -  isoleucyl-tRNA synthetase

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK0027, JW0024, ilvS
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  1. Relationship of protein structure of isoleucyl-tRNA synthetase with pseudomonic acid resistance of Escherichia coli. A proposed mode of action of pseudomonic acid as an inhibitor of isoleucyl-tRNA synthetase. Yanagisawa, T., Lee, J.T., Wu, H.C., Kawakami, M. J. Biol. Chem. (1994) [Pubmed]
  2. The type II signal peptidase of Legionella pneumophila. Geukens, N., De Buck, E., Meyen, E., Maes, L., Vranckx, L., Van Mellaert, L., Ann??, J., Lammertyn, E. Res. Microbiol. (2006) [Pubmed]
  3. Crystal structures of the CP1 domain from Thermus thermophilus isoleucyl-tRNA synthetase and its complex with L-valine. Fukunaga, R., Fukai, S., Ishitani, R., Nureki, O., Yokoyama, S. J. Biol. Chem. (2004) [Pubmed]
  4. A eubacterial Mycobacterium tuberculosis tRNA synthetase is eukaryote-like and resistant to a eubacterial-specific antisynthetase drug. Sassanfar, M., Kranz, J.E., Gallant, P., Schimmel, P., Shiba, K. Biochemistry (1996) [Pubmed]
  5. The valyl-tRNA synthetase from Bacillus stearothermophilus has considerable sequence homology with the isoleucyl-tRNA synthetase from Escherichia coli. Borgford, T.J., Brand, N.J., Gray, T.E., Fersht, A.R. Biochemistry (1987) [Pubmed]
  6. Artificially ambiguous genetic code confers growth yield advantage. Pezo, V., Metzgar, D., Hendrickson, T.L., Waas, W.F., Hazebrouck, S., Döring, V., Marlière, P., Schimmel, P., De Crécy-Lagard, V. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  7. Misactivated amino acids translocate at similar rates across surface of a tRNA synthetase. Nomanbhoy, T.K., Schimmel, P.R. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  8. Dominant lethality by expression of a catalytically inactive class I tRNA synthetase. Schmidt, E., Schimmel, P. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  9. Identification of Saccharomyces cerevisiae isoleucyl-tRNA synthetase as a target of the G1-specific inhibitor Reveromycin A. Miyamoto, Y., Machida, K., Mizunuma, M., Emoto, Y., Sato, N., Miyahara, K., Hirata, D., Usui, T., Takahashi, H., Osada, H., Miyakawa, T. J. Biol. Chem. (2002) [Pubmed]
  10. Mechanism of mupirocin transport into sensitive and resistant bacteria. Capobianco, J.O., Doran, C.C., Goldman, R.C. Antimicrob. Agents Chemother. (1989) [Pubmed]
  11. Isoleucyl-tRNA synthetase of Methanobacterium thermoautotrophicum Marburg. Cloning of the gene, nucleotide sequence, and localization of a base change conferring resistance to pseudomonic acid. Jenal, U., Rechsteiner, T., Tan, P.Y., Bühlmann, E., Meile, L., Leisinger, T. J. Biol. Chem. (1991) [Pubmed]
  12. The signal peptidase II (Isp) gene of Bacillus subtilis. Prágai, Z., Tjalsma, H., Bolhuis, A., van Dijl, J.M., Venema, G., Bron, S. Microbiology (Reading, Engl.) (1997) [Pubmed]
  13. Cloning and sequence determination of the acetohydroxy acid synthase genes from Brevibacterium flavum MJ233 by using the polymerase chain reaction. Inui, M., Vertès, A.A., Kobayashi, M., Kurusu, Y., Yukawa, H. DNA Seq. (1993) [Pubmed]
  14. Interfering with different steps of protein synthesis explored by transcriptional profiling of Escherichia coli K-12. Sabina, J., Dover, N., Templeton, L.J., Smulski, D.R., Söll, D., LaRossa, R.A. J. Bacteriol. (2003) [Pubmed]
  15. Amino acid selectivity in the aminoacylation of coenzyme A and RNA minihelices by aminoacyl-tRNA synthetases. Jakubowski, H. J. Biol. Chem. (2000) [Pubmed]
  16. Editing mechanisms in protein synthesis. Rejection of valine by the isoleucyl-tRNA synthetase. Fersht, A.R. Biochemistry (1977) [Pubmed]
  17. Proofreading in trans by an aminoacyl-tRNA synthetase: a model for single site editing by isoleucyl-tRNA synthetase. Jakubowski, H. Nucleic Acids Res. (1996) [Pubmed]
  18. Isolation of temperature-sensitive aminoacyl-tRNA synthetase mutants from an Escherichia coli strain harboring the pemK plasmid. Masuda, Y., Tsuchimoto, S., Nishimura, A., Ohtsubo, E. Mol. Gen. Genet. (1993) [Pubmed]
  19. Synthesis and activities of branched-chain aminoacyl-tRNA synthetases in threonine deaminase mutants of Escherichia coli. Williams, A.L., Whitfield, S.M., Williams, L.S. J. Bacteriol. (1978) [Pubmed]
  20. Studies of the interaction between aminoacyl-tRNA synthetase and transfer ribonucleic acid by equilibrium partition. Hustedt, H., Kula, M.R. Eur. J. Biochem. (1977) [Pubmed]
  21. Effects of a minor isoleucyl tRNA on heterologous protein translation in Escherichia coli. Del Tito, B.J., Ward, J.M., Hodgson, J., Gershater, C.J., Edwards, H., Wysocki, L.A., Watson, F.A., Sathe, G., Kane, J.F. J. Bacteriol. (1995) [Pubmed]
  22. The pAX plasmids: new gene-fusion vectors for sequencing, mutagenesis and expression of proteins in Escherichia coli. Markmeyer, P., Rühlmann, A., Englisch, U., Cramer, F. Gene (1990) [Pubmed]
  23. Crystallization and preliminary X-ray crystallographic study of the editing domain of Thermus thermophilus isoleucyl-tRNA synthetase complexed with pre- and post-transfer editing-substrate analogues. Fukunaga, R., Yokoyama, S. Acta Crystallogr. D Biol. Crystallogr. (2004) [Pubmed]
  24. Analysis of protein sequences and protein complexes by matrix-assisted laser desorption/ionization mass spectrometry. Belghazi, M., Bathany, K., Hountondji, C., Grandier-Vazeille, X., Manon, S., Schmitter, J.M. Proteomics (2001) [Pubmed]
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