Disease relevance of Antimony sulfide

• METHODS: Patients with anal squamous-cell carcinoma had four injections of 0.2 ml of antimony sulfide (30 MBq) around the tumor [1].
• Radionuclide lymphoscintigraphy with technetium 99m antimony sulfide colloid to identify lymphatic drainage of cutaneous melanoma at ambiguous sites in the head and neck and trunk [2].
• As judged by leakage of colloidal antimony sulfide (Sb2S3), thrombocytopenia in rats does not alter the normal permeability of small blood vessels in skin or bowel mucosa or modify the magnitude of increased permeability in skin vessels induced by histamine or by mild thermal injury [3].

High impact information on Antimony sulfide

• The results indicated a statistical difference between agents; Tc-99m antimony sulfide allowed visualization of a greater number of more intense nodes, better delineation of the total length of the internal mammary lymph-node chain, and a more consistent visualization of supraclavicular nodes [4].
• Technetium-99m antimony sulfide colloid and indium-113m hydroxide were then examined by electron microscopy, and the chemical nature of the particles was determined by x-ray fluorescence analysis [5].
• After surgical exposure, approximately 500 microCi of 99mTc-labelled antimony sulfide was injected into the myocardium or the adventitial-medial plane of an artery [6].
• Preoperative lymphoscintigraphy with Tc-99m antimony sulfide colloid was performed in a patient with cutaneous melanoma on the lower back just to the right of the midline [7].

Associations of Antimony sulfide with other chemical compounds

• Lymphoscintigrams were performed by a circumferential intradermal injection of the biopsy site using technetium 99m (99mTc) antimony sulfide colloid in a total dose of 0.2 to 0.6 mCi in a volume of 0.1 to 0.5 ml [2].

Analytical, diagnostic and therapeutic context of Antimony sulfide

• After intraventricular injection of 99mTc antimony sulfide in rabbits (n = 12) and cats (n = 14), radiolabeled colloid was imaged passing into the nasal mucosa and subsequently into the cervical lymph nodes [8].
• It was concluded that preoperative 99mTc antimony sulfide lymphoscintigraphy is a highly useful planning technique in determining the appropriate lymphatic drainage basin for dissection in selected melanoma patients [2].

References