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Chemical Compound Review:

Diopside calcium; dihydroxy-oxo-silane; magnesium

Synonyms: AC1O3SRU, Camg(sio3)2, 14483-19-3, Diopside (CaMg(SiO3)2), calcium; dihydroxy(oxo)silane; magnesium

Miake, Y. et al., Kobayashi, T. et al., Qian, G. et al., Olsen, E.J. et al., De Aza, P.N. et al., et al.

De Aza, Luklinska, Anseau, Qian, Song, Zhang, Xia, Zhang, Chui, Nonami, Tsutsumi,

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Disease relevance of Diopside

It was proved that diopside has no general toxicity in cell culture [1].

High impact information on Diopside

A silicate inclusion within the IIIA meteorite Puente del Zacate consisting of olivine (Fa4), low-calcium pyroxene (Fs6Wo1), chromium diopside (Fs3Wo47), plagioclase (An14Or4), graphite, troilite, chromite, daubreelite, and iron metal resembles inclusions in IAB iron meteorites [2].
Specimens were prepared in three experiments: (1) Granular diopside was immersed in simulated body fluid (SBF); (2) granular diopside was implanted into a cavity in rabbit bone; and (3) a diopside dental root implant was implanted into a Japanese monkey [3].
By thermal treatments of G13, a glass-ceramic (GC13) containing apatite, diopside, althausite and akermanite as crystalline phases was developed [4].
In order to clarify the biocompatibility of Diopside, the cytotoxicity of Diopside against the osteogenic cell line MC3T3-E1 and the bone-Diopside interface strength were examined [5].
On both the 14th and 21st days of incubation of MC3T3-E1 cells with Diopside, ALP activities were not significantly lower than those of the CTRL [5].

Biological context of Diopside

By utilising MSW fly ash from the Shanghai Yuqiao municipal solid waste (MSW) incineration plant as the main raw material, diopside-based glass-ceramics were successfully synthesized in the laboratory by combining SiO(2), MgO and Al(2)O(3) or bottom ash as conditioner of the chemical compositions and TiO(2) as the nucleation agent [6].

Gene context of Diopside

Osteogenic cell cytotoxicity and biomechanical strength of the new ceramic Diopside [5].
Changes in ionic concentrations were measured using Inductively Coupled Plasma Atomic Emission Spectroscopy (ICP-AES), while the pH right at the interface of diopside/PHS were determined with an Ion Sensitive Field Effect Transistor (ISFET-Meter) instruments [7].
Spinel and diopside in the CAI cores are 16O-rich (Delta17O up to -20 per thousand), whereas diopside in their outer zones, as well as melilite and anorthite, are 16O-depleted (Delta17O = -8 per thousand to 2 per thousand) [8].

Analytical, diagnostic and therapeutic context of Diopside

High-resolution transmission electron microscopy revealed crystal growth from the diopside surface layer, and continuity between the diopside lattice and that of the new crystals [3].
In the experiments which used a rabbit and a monkey, contact microradiography showed close contact between bone and diopside [3].
Crystallization of diopside of this glass is controlled by volume nucleation and growth processes [9].

References

Study of diopside ceramics for biomaterials. Nonami, T., Tsutsumi, S. Journal of materials science. Materials in medicine. (1999) [Pubmed]
A silicate inclusion in Puente del Zacate, a IIIA iron meteorite. Olsen, E.J., Davis, A.M., Clayton, R.N., Mayeda, T.K., Moore, C.B., Steele, I.M. Science (1996) [Pubmed]
High-resolution and analytical electron microscopic studies of new crystals induced by a bioactive ceramic (diopside). Miake, Y., Yanagisawa, T., Yajima, Y., Noma, H., Yasui, N., Nonami, T. J. Dent. Res. (1995) [Pubmed]
In vitro bioactivity of glass and glass-ceramics of the 3CaO x P2O5-CaO x SiO2-CaO x MgO x 2SiO2 system. Salinas, A.J., Román, J., Vallet-Regí, M., Oliveira, J.M., Correia, R.N., Fernandes, M.H. Biomaterials (2000) [Pubmed]
Osteogenic cell cytotoxicity and biomechanical strength of the new ceramic Diopside. Kobayashi, T., Okada, K., Kuroda, T., Sato, K. J. Biomed. Mater. Res. (1997) [Pubmed]
Diopside-based glass-ceramics from MSW fly ash and bottom ash. Qian, G., Song, Y., Zhang, C., Xia, Y., Zhang, H., Chui, P. Waste management (New York, N.Y.) (2006) [Pubmed]
Bioactivity of diopside ceramic in human parotid saliva. De Aza, P.N., Luklinska, Z.B., Anseau, M. Journal of biomedical materials research. Part B, Applied biomaterials. (2005) [Pubmed]
Chronology of the early Solar System from chondrule-bearing calcium-aluminium-rich inclusions. Krot, A.N., Yurimoto, H., Hutcheon, I.D., MacPherson, G.J. Nature (2005) [Pubmed]
Press-formable CaO-MgO-SiO(2)-TiO(2)-Ag(2)O glass as a biomaterial. Nonami, T., Tsutsumi, S. J. Biomed. Mater. Res. (2000) [Pubmed]

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