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Chemical Compound Review

Lysosulfatide     sodium(2R,3R,4S,5S,6R)-2- [(E,2S,3R)-2...

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Disease relevance of (2R,3R,4S,5S,6R)-2-[(E,2S,3R)-2-amino-3-hydroxy-octadec-4-enoxy]-3,5-dihydroxy-6-methylol-4-sulfoxy-tetrahydropyran


High impact information on (2R,3R,4S,5S,6R)-2-[(E,2S,3R)-2-amino-3-hydroxy-octadec-4-enoxy]-3,5-dihydroxy-6-methylol-4-sulfoxy-tetrahydropyran


Associations of (2R,3R,4S,5S,6R)-2-[(E,2S,3R)-2-amino-3-hydroxy-octadec-4-enoxy]-3,5-dihydroxy-6-methylol-4-sulfoxy-tetrahydropyran with other chemical compounds


Analytical, diagnostic and therapeutic context of (2R,3R,4S,5S,6R)-2-[(E,2S,3R)-2-amino-3-hydroxy-octadec-4-enoxy]-3,5-dihydroxy-6-methylol-4-sulfoxy-tetrahydropyran


  1. Lysosulfatide (galactosylsphingosine-3-O-sulfate) from metachromatic leukodystrophy and normal human brain. Rosengren, B., Fredman, P., Månsson, J.E., Svennerholm, L. J. Neurochem. (1989) [Pubmed]
  2. Lysosulfatide (sulfogalactosylsphingosine) accumulation in tissues from patients with metachromatic leukodystrophy. Toda, K., Kobayashi, T., Goto, I., Ohno, K., Eto, Y., Inui, K., Okada, S. J. Neurochem. (1990) [Pubmed]
  3. Accumulation of lysosulfatide (sulfogalactosylsphingosine) in tissues of a boy with metachromatic leukodystrophy. Toda, K., Kobayashi, T., Goto, I., Kurokawa, T., Ogomori, K. Biochem. Biophys. Res. Commun. (1989) [Pubmed]
  4. High density lipoprotein-associated lysosphingolipids reduce E-selectin expression in human endothelial cells. Nofer, J.R., Geigenmüller, S., Göpfert, C., Assmann, G., Buddecke, E., Schmidt, A. Biochem. Biophys. Res. Commun. (2003) [Pubmed]
  5. HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3. Nofer, J.R., van der Giet, M., Tölle, M., Wolinska, I., von Wnuck Lipinski, K., Baba, H.A., Tietge, U.J., Gödecke, A., Ishii, I., Kleuser, B., Schäfers, M., Fobker, M., Zidek, W., Assmann, G., Chun, J., Levkau, B. J. Clin. Invest. (2004) [Pubmed]
  6. Suppression of endothelial cell apoptosis by high density lipoproteins (HDL) and HDL-associated lysosphingolipids. Nofer, J.R., Levkau, B., Wolinska, I., Junker, R., Fobker, M., von Eckardstein, A., Seedorf, U., Assmann, G. J. Biol. Chem. (2001) [Pubmed]
  7. Activation of phosphatidylinositol-specific phospholipase C by HDL-associated lysosphingolipid. Involvement in mitogenesis but not in cholesterol efflux. Nofer, J.R., Fobker, M., Höbbel, G., Voss, R., Wolinska, I., Tepel, M., Zidek, W., Junker, R., Seedorf, U., von Eckardstein, A., Assmann, G., Walter, M. Biochemistry (2000) [Pubmed]
  8. New approach for characterization of lysosulfatide by TLC, fast atom bombardment mass spectrometry and NMR spectroscopy. Taketomi, T., Hara, A., Kutsukake, Y., Sugiyama, E. J. Biochem. (1990) [Pubmed]
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