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Chemical Compound Review

AC1NSKNF     2-[[(E,2R,3S)-2-amino-3- hydroxy-octadec-4...

Synonyms:
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Disease relevance of 2-[[(E,2R,3S)-2-amino-3-hydroxy-octadec-4-enoxy]-hydroxy-phosphoryl]oxyethyl-trimethyl-azanium

 

High impact information on 2-[[(E,2R,3S)-2-amino-3-hydroxy-octadec-4-enoxy]-hydroxy-phosphoryl]oxyethyl-trimethyl-azanium

 

Chemical compound and disease context of 2-[[(E,2R,3S)-2-amino-3-hydroxy-octadec-4-enoxy]-hydroxy-phosphoryl]oxyethyl-trimethyl-azanium

 

Biological context of 2-[[(E,2R,3S)-2-amino-3-hydroxy-octadec-4-enoxy]-hydroxy-phosphoryl]oxyethyl-trimethyl-azanium

 

Anatomical context of 2-[[(E,2R,3S)-2-amino-3-hydroxy-octadec-4-enoxy]-hydroxy-phosphoryl]oxyethyl-trimethyl-azanium

 

Associations of 2-[[(E,2R,3S)-2-amino-3-hydroxy-octadec-4-enoxy]-hydroxy-phosphoryl]oxyethyl-trimethyl-azanium with other chemical compounds

 

Gene context of 2-[[(E,2R,3S)-2-amino-3-hydroxy-octadec-4-enoxy]-hydroxy-phosphoryl]oxyethyl-trimethyl-azanium

 

Analytical, diagnostic and therapeutic context of 2-[[(E,2R,3S)-2-amino-3-hydroxy-octadec-4-enoxy]-hydroxy-phosphoryl]oxyethyl-trimethyl-azanium

References

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  3. Sphingosylphosphorylcholine is upregulated in the stratum corneum of patients with atopic dermatitis. Okamoto, R., Arikawa, J., Ishibashi, M., Kawashima, M., Takagi, Y., Imokawa, G. J. Lipid Res. (2003) [Pubmed]
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  25. Sphingosylphosphorylcholine stimulates proliferation and upregulates cell surface-associated plasminogen activator activity in cultured human keratinocytes. Wakita, H., Matsushita, K., Nishimura, K., Tokura, Y., Furukawa, F., Takigawa, M. J. Invest. Dermatol. (1998) [Pubmed]
  26. Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6. Van Brocklyn, J.R., Gräler, M.H., Bernhardt, G., Hobson, J.P., Lipp, M., Spiegel, S. Blood (2000) [Pubmed]
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  28. Sphingosylphosphorylcholine-induced ERK activation inhibits melanin synthesis in human melanocytes. Kim, D.S., Park, S.H., Kwon, S.B., Park, E.S., Huh, C.H., Youn, S.W., Park, K.C. Pigment Cell Res. (2006) [Pubmed]
  29. EDG3 is a functional receptor specific for sphingosine 1-phosphate and sphingosylphosphorylcholine with signaling characteristics distinct from EDG1 and AGR16. Okamoto, H., Takuwa, N., Yatomi, Y., Gonda, K., Shigematsu, H., Takuwa, Y. Biochem. Biophys. Res. Commun. (1999) [Pubmed]
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