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Chemical Compound Review

Transfluthrin     (2,3,5,6- tetrafluorophenyl)methyl (1R,3S)...

Synonyms: AC1LCVAG, CHEBI:32253, AKOS015899270, Tox21_112675, C13410, ...
 
 
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High impact information on C13410

  • In rats exposed to mosquito coil smoke containing transfluthrin, a somewhat increased frequency of alveolar macrophages with foamy appearance was identified through cytodifferentiation but not histopathology compared with the blank coil [1].
  • A total of 449 pregnant women were prospectively recruited at midgestation from an agricultural site in the Philippines where a preliminary survey indicated significant use at home and on the farm of the following compounds: propoxur, cyfluthrin, chlorpyrifos, cypermethrin, pretilachlor, bioallethrin, malathion, diazinon, and transfluthrin [2].
  • The concentration of 0.1% transfluthrin in vegetable oil gave 50-75% reduction in biting, a similar degree of protection to that obtained from burning a mosquito coil containing a synthetic pyrethroid (0.25% d-allethrin) and significantly better protection than a locally bought coil (brand 'White Crane', probably containing DDT) [3].

References

  1. Mosquito coil smoke inhalation toxicity. Part II: subchronic nose-only inhalation study in rats. Pauluhn, J., Mohr, U. Journal of applied toxicology : JAT. (2006) [Pubmed]
  2. Maternal hair--an appropriate matrix for detecting maternal exposure to pesticides during pregnancy. Ostrea, E.M., Villanueva-Uy, E., Bielawski, D.M., Posecion, N.C., Corrion, M.L., Jin, Y., Janisse, J.J., Ager, J.W. Environmental research. (2006) [Pubmed]
  3. Personal protection against mosquitoes in Dar es Salaam, Tanzania, by using a kerosene oil lamp to vaporize transfluthrin. Pates, H.V., Line, J.D., Keto, A.J., Miller, J.E. Med. Vet. Entomol. (2002) [Pubmed]
 
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