Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Aromadedrin 3,5,7-trihydroxy-2-(4- hydroxyphenyl)chroma...

Synonyms: Aromadendrol, SureCN39319, AGN-PC-009BX8, AG-G-85152, AG-J-60539, ...

Meyer, P. et al., Masuzaki, S. et al., Brugliera, F. et al., Ryan, K.G. et al., Owens, D.K. et al.

Brugliera, Barri-Rewell, Holton, Mason, Ryan, Swinny, Winefield, Markham,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on dihydrokaempferol

This is due to the substrate specificity of the dihydroflavonol 4-reductase of petunia, which cannot reduce dihydrokaempferol [1].
RL01 served as a recipient for the transfer of the A1 gene of Zea mays encoding dihydroquercetin 4-reductase, which can reduce dihydrokaempferol and thereby provided the intermediate for pelargonidin biosynthesis [1].
We have isolated a cDNA clone that corresponds to the Ht1 locus of petunia which controls the hydroxylation of dihydrokaempferol to dihydroquercetin and of naringenin to eriodictyol by the action of flavonoid 3'-hydroxylase (F3'H) [2].
Direct comparison between genomic constitution and flavonoid contents in Allium multiple alien addition lines reveals chromosomal locations of genes related to biosynthesis from dihydrokaempferol to quercetin glucosides in scaly leaf of shallot (Allium cepa L.) [3].
These results suggest that flavonols protect Arabidopsis plants from UVB damage, and indicate that the flavonoid 3'-hydroxylase (F3'H) enzyme, which converts dihydrokaempferol to dihydroquercetin, may play a crucial role [4].

Analytical, diagnostic and therapeutic context of dihydrokaempferol

Quantification of the production of dihydrokaempferol by flavanone 3-hydroxytransferase using capillary electrophoresis [5].

References

A new petunia flower colour generated by transformation of a mutant with a maize gene. Meyer, P., Heidmann, I., Forkmann, G., Saedler, H. Nature (1987) [Pubmed]
Isolation and characterization of a flavonoid 3'-hydroxylase cDNA clone corresponding to the Ht1 locus of Petunia hybrida. Brugliera, F., Barri-Rewell, G., Holton, T.A., Mason, J.G. Plant J. (1999) [Pubmed]
Direct comparison between genomic constitution and flavonoid contents in Allium multiple alien addition lines reveals chromosomal locations of genes related to biosynthesis from dihydrokaempferol to quercetin glucosides in scaly leaf of shallot (Allium cepa L.). Masuzaki, S., Shigyo, M., Yamauchi, N. Theor. Appl. Genet. (2006) [Pubmed]
Flavonoids and UV photoprotection in Arabidopsis mutants. Ryan, K.G., Swinny, E.E., Winefield, C., Markham, K.R. Z. Naturforsch., C, J. Biosci. (2001) [Pubmed]
Quantification of the production of dihydrokaempferol by flavanone 3-hydroxytransferase using capillary electrophoresis. Owens, D.K., Hale, T., Wilson, L.J., McIntosh, C.A. Phytochemical analysis : PCA. (2002) [Pubmed]

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