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Gene Review

catA  -  catechol 1,2-dioxygenase

Pseudomonas putida KT2440

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Disease relevance of catA

  • The catA gene, encoding the major CatA from a root-colonizing isolate Pseudomonas putida (Pp), was cloned by complementation into a catalase (Cat)-deficient Escherichia coli (Ec) strain UM2 [1].
  • The relationship between the pheB gene and other C12O-encoding genes has been shown: comparison of the pheB sequence with sequences of catA of Alcaligenes calcoaceticus, tfdC of A. eutrophus and clcA of P. putida demonstrated that there are conserved residues in all the four protein products of these genes [2].
  • Crude extracts of Escherichia coli cells carrying the catA gene downstream from the lac promoter showed the enzyme activity [3].

High impact information on catA


Associations of catA with chemical compounds


Analytical, diagnostic and therapeutic context of catA

  • We have cloned a catA gene from Pseudomonas putida mt-2 using a PCR product of amino acid sequence-based primers as a probe [3].


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