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Gene Review

Skts1  -  skin tumor susceptibility 1

Mus musculus

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Disease relevance of Skts1


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Biological context of Skts1


  1. Allele-specific Hras mutations and genetic alterations at tumor susceptibility loci in skin carcinomas from interspecific hybrid mice. Nagase, H., Mao, J.H., Balmain, A. Cancer Res. (2003) [Pubmed]
  2. Use of intercross outbred mice and single nucleotide polymorphisms to map skin cancer modifier loci. Peissel, B., Zaffaroni, D., Pazzaglia, S., Manenti, G., Zanesi, N., Zedda, I., Rebessi, S., Covelli, V., Dragani, T.A., Saran, A. Mamm. Genome (2001) [Pubmed]
  3. Loss of collagenase-2 confers increased skin tumor susceptibility to male mice. Balbín, M., Fueyo, A., Tester, A.M., Pendás, A.M., Pitiot, A.S., Astudillo, A., Overall, C.M., Shapiro, S.D., López-Otín, C. Nat. Genet. (2003) [Pubmed]
  4. Genetic variants of Tgfb1 act as context-dependent modifiers of mouse skin tumor susceptibility. Mao, J.H., Saunier, E.F., de Koning, J.P., McKinnon, M.M., Higgins, M.N., Nicklas, K., Yang, H.T., Balmain, A., Akhurst, R.J. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
  5. Epistatic interactions between skin tumor modifier loci in interspecific (spretus/musculus) backcross mice. Nagase, H., Mao, J.H., de Koning, J.P., Minami, T., Balmain, A. Cancer Res. (2001) [Pubmed]
  6. Loss of tyrosinase activity confers increased skin tumor susceptibility in mice. Saran, A., Spinola, M., Pazzaglia, S., Peissel, B., Tiveron, C., Tatangelo, L., Mancuso, M., Covelli, V., Giovannelli, L., Pitozzi, V., Pignatiello, C., Milani, S., Dolara, P., Dragani, T.A. Oncogene (2004) [Pubmed]
  7. Identification of an X-linked locus modifying mouse skin tumor susceptibility. George, K., Iacobucci, A., Uitto, J., O'Brien, T.G. Mol. Carcinog. (2005) [Pubmed]
  8. Genetic control of polyamine-dependent susceptibility to skin tumorigenesis. Megosh, L.C., Hu, J., George, K., O'Brien, T.G. Genomics (2002) [Pubmed]
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