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Gene Review

SPATA4  -  spermatogenesis associated 4

Homo sapiens

Synonyms: SPEF1B, Spermatogenesis-associated protein 4, TSARG2, Testis and spermatogenesis cell-related protein 2, Testis spermatocyte apoptosis-related gene 2 protein
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Disease relevance of SPATA4


High impact information on SPATA4


Anatomical context of SPATA4


Analytical, diagnostic and therapeutic context of SPATA4

  • According to the RT-PCR results, no expression of SPATA4 is detected until the rat is 30 d old after birth [2].
  • Northern blot analysis revealed that 1.7 kb TSARG2 transcript was detected selectively in human testis [1].


  1. Cloning of a full-length cDNA of human testis-specific spermatogenic cell apoptosis inhibitor TSARG2 as a candidate oncogene. Liu, S.F., Lu, G.X., Liu, G., Xing, X.W., Li, L.Y., Wang, Z. Biochem. Biophys. Res. Commun. (2004) [Pubmed]
  2. Cloning and characterization of testis-specific spermatogenesis associated gene homologous to human SPATA4 in rat. Liu, S.F., He, S., Liu, B.W., Zhao, Y., Wang, Z. Biol. Pharm. Bull. (2004) [Pubmed]
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