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Gene Review

Ugdh  -  UDP-glucose dehydrogenase

Mus musculus

Synonyms: UDP-Glc dehydrogenase, UDP-GlcDH, UDP-glucose 6-dehydrogenase, UDPGDH, Udpgdh
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High impact information on Ugdh


Analytical, diagnostic and therapeutic context of Ugdh

  • By RT-PCR the presence of transcripts for several genes involved in the synthesis of HA in normal and autoimmune kidneys could be demonstrated, including mRNA for UDPGDH and HAS1 and HAS2, but not for HAS3 [6].
  • A new HPLC assay was developed to measure UDP-glucose dehydrogenase (UDP-GDH) activity in crude homogenates of 3T3 fibroblasts [4].


  1. Effect of volatile anesthetics on the hepatic UDP-glucuronic acid pathway in mice. Watkins, J.B., Engles, D.R., Beck, L.V. Biochem. Pharmacol. (1990) [Pubmed]
  2. Metabolism of the amino acid beta-pyrazol-1-ylalanine and its parent base pyrazole. Al-Baldawi, N.F., Brown, E.G. Biochem. Pharmacol. (1985) [Pubmed]
  3. Tissue- and Gender-Specific mRNA Expression of UDP-Glucuronosyltransferases (UGTs) in Mice. Buckley, D.B., Klaassen, C.D. Drug Metab. Dispos. (2007) [Pubmed]
  4. Serum stimulation of UDP-glucose dehydrogenase activity in Swiss 3T3 fibroblasts. Grubb, M.F., Kasofsky, J., Strong, J., Anderson, L.W., Cysyk, R.L. Biochem. Mol. Biol. Int. (1993) [Pubmed]
  5. Comparative effects of dietary administration of antioxidants and inducers on the activities of several hepatic enzymes in mice. Cha, Y.N., Heine, H.S., Ansher, S. Drug-nutrient interactions. (1983) [Pubmed]
  6. Enhanced hyaluronan synthesis in the MRL-Fas(lpr) kidney: role of cytokines. Feusi, E., Sun, L., Sibalic, A., Beck-Schimmer, B., Oertli, B., Wüthrich, R.P. Nephron (1999) [Pubmed]
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