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Gene Review

BICD2  -  bicaudal D homolog 2 (Drosophila)

Homo sapiens

Synonyms: Bic-D 2, KIAA0699, Protein bicaudal D homolog 2, SMALED2, bA526D8.1
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High impact information on BICD2


Biological context of BICD2


  1. Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex. Matanis, T., Akhmanova, A., Wulf, P., Del Nery, E., Weide, T., Stepanova, T., Galjart, N., Grosveld, F., Goud, B., De Zeeuw, C.I., Barnekow, A., Hoogenraad, C.C. Nat. Cell Biol. (2002) [Pubmed]
  2. Bicaudal D induces selective dynein-mediated microtubule minus end-directed transport. Hoogenraad, C.C., Wulf, P., Schiefermeier, N., Stepanova, T., Galjart, N., Small, J.V., Grosveld, F., de Zeeuw, C.I., Akhmanova, A. EMBO J. (2003) [Pubmed]
  3. Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes. Hoogenraad, C.C., Akhmanova, A., Howell, S.A., Dortland, B.R., De Zeeuw, C.I., Willemsen, R., Visser, P., Grosveld, F., Galjart, N. EMBO J. (2001) [Pubmed]
  4. Purification, cloning, and characterization of Nek8, a novel NIMA-related kinase, and its candidate substrate Bicd2. Holland, P.M., Milne, A., Garka, K., Johnson, R.S., Willis, C., Sims, J.E., Rauch, C.T., Bird, T.A., Virca, G.D. J. Biol. Chem. (2002) [Pubmed]
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