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Gene Review

ACAP2  -  ArfGAP with coiled-coil, ankyrin repeat...

Homo sapiens

Synonyms: Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2, CENTB2, CNT-B2, Centaurin-beta-2, Cnt-b2, ...
 
 
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Disease relevance of CENTB2

  • Vaccinia virus K1L protein supports viral replication in human and rabbit cells through a cell-type-specific set of its ankyrin repeat residues that are distinct from its binding site for ACAP2 [1].
 

High impact information on CENTB2

References

  1. Vaccinia virus K1L protein supports viral replication in human and rabbit cells through a cell-type-specific set of its ankyrin repeat residues that are distinct from its binding site for ACAP2. Meng, X., Xiang, Y. Virology (2006) [Pubmed]
  2. ACAPs are arf6 GTPase-activating proteins that function in the cell periphery. Jackson, T.R., Brown, F.D., Nie, Z., Miura, K., Foroni, L., Sun, J., Hsu, V.W., Donaldson, J.G., Randazzo, P.A. J. Cell Biol. (2000) [Pubmed]
  3. Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1. Nomura, N., Nagase, T., Miyajima, N., Sazuka, T., Tanaka, A., Sato, S., Seki, N., Kawarabayasi, Y., Ishikawa, K., Tabata, S. DNA Res. (1994) [Pubmed]
 
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