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Gene Review

FJX1  -  four jointed box 1 (Drosophila)

Homo sapiens

Synonyms: FLJ22416, FLJ25593, Four-jointed box protein 1, Four-jointed protein homolog
 
 
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High impact information on FJX1

  • In addition to the previously described expression of fjx1 in mouse brain, we show here that fjx1 is expressed in the peripheral nervous system, epithelial cells of multiple organs, and during limb development [1].
  • In the neural plate, fjx1 is expressed in the presumptive forebrain and midbrain, and in rhombomere 4, however a small rostral/medial area of the forebrain primordium is devoid of expression [2].
  • (3) In the adult, fjx1 is expressed by neurones evenly distributed in the telencephalon (isocortex, striatum, hippocampus, olfactory bulb, piriform cortex), in the Purkinje cell layer of the cerebellum, and numerous medullary nuclei [2].
  • Here we report the cloning of the mouse four-jointed gene (fjx1) and its pattern of expression in the brain during embryogenesis and in the adult [2].
 

Anatomical context of FJX1

  • (1) In the embryonic brain fjx1 is expressed in two patches of neuroepithelium: in the midbrain tectum and the telencephalic vesicles [2].

References

 
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