Gene Review:
RL1 - virion protein; inhibits stress-induced...
Human herpesvirus 1
- Status of the ICP34.5 gene in herpes simplex virus type 1 strain 17. Dolan, A., McKie, E., MacLean, A.R., McGeoch, D.J. J. Gen. Virol. (1992)
- Characterization of the herpes simplex virus type 1 strain 17+ neurovirulence gene RL1 and its expression in a bacterial system. McKie, E.A., Hope, R.G., Brown, S.M., MacLean, A.R. J. Gen. Virol. (1994)
- Functional analysis of the herpes simplex virus type 2 strain HG52 RL1 gene: the intron plays no role in virulence. Ravi, V., Kennedy, P.G., MacLean, A.R. J. Gen. Virol. (1998)
- Complete genome sequence of cercopithecine herpesvirus 2 (SA8) and comparison with other simplexviruses. Tyler, S.D., Peters, G.A., Severini, A. Virology (2005)
- Selective internalization of sodium channels in rat dorsal root ganglion neurons infected with herpes simplex virus-1. Storey, N., Latchman, D., Bevan, S. J. Cell Biol. (2002)
- The complete genome sequence of herpesvirus papio 2 (Cercopithecine herpesvirus 16) shows evidence of recombination events among various progenitor herpesviruses. Tyler, S.D., Severini, A. J. Virol. (2006)
- ICP34.5 deleted herpes simplex virus with enhanced oncolytic, immune stimulating, and anti-tumour properties. Liu, B.L., Robinson, M., Han, Z.Q., Branston, R.H., English, C., Reay, P., McGrath, Y., Thomas, S.K., Thornton, M., Bullock, P., Love, C.A., Coffin, R.S. Gene Ther. (2003)
- Selective astrocytic transgene expression in vitro and in vivo from the GFAP promoter in a HSV RL1 null mutant vector--potential glioblastoma targeting. McKie, E.A., Graham, D.I., Brown, S.M. Gene Ther. (1998)
- A virus with a mutation in the ICP4-binding site in the L/ST promoter of herpes simplex virus type 1, but not a virus with a mutation in open reading frame P, exhibits cell-type-specific expression of gamma(1)34.5 transcripts and latency-associated transcripts. Lee, L.Y., Schaffer, P.A. J. Virol. (1998)
- The herpes simplex virus type 1 strain 17 open reading frame RL1 encodes a polypeptide of apparent M(r) 37K equivalent to ICP34.5 of herpes simplex virus type 1 strain F. McKay, E.M., McVey, B., Marsden, H.S., Brown, S.M., MacLean, A.R. J. Gen. Virol. (1993)
- Cell type and cell state determine differential in vitro growth of non-neurovirulent ICP34.5-negative herpes simplex virus types 1 and 2. Brown, S.M., Harland, J., MacLean, A.R., Podlech, J., Clements, J.B. J. Gen. Virol. (1994)
- Selective in vitro replication of herpes simplex virus type 1 (HSV-1) ICP34.5 null mutants in primary human CNS tumours--evaluation of a potentially effective clinical therapy. McKie, E.A., MacLean, A.R., Lewis, A.D., Cruickshank, G., Rampling, R., Barnett, S.C., Kennedy, P.G., Brown, S.M. Br. J. Cancer (1996)
- Toxicity and neuronal infection of a HSV-1 ICP34.5 mutant in nude mice. Lasner, T.M., Tal-Singer, R., Kesari, S., Lee, V.M., Trojanowski, J.Q., Fraser, N.W. J. Neurovirol. (1998)
- Replication of the herpes simplex virus type 1 RL1 mutant 1716 in primary neuronal cell cultures--possible relevance to use as a viral vector. Kennedy, P.G., Gairns, J., MacLean, A.R. J. Neurol. Sci. (2000)