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Gene Review:

CD34 - CD34 molecule

Bos taurus

Zhou, J.H. et al., Sarac, T.P. et al., Zhang, Y. et al.

Sarac, Carnevale, Smedira, Tanquilut, Augustinos, Patel, Naska, Clair, Ouriel,

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High impact information on CD34

Immunofluorescence for CD34 and Factor VIII demonstrated complete re-endothelialization of all patches [1].
Immunofluorescence for CD 34 and Factor VIII was done to evaluate endothelialization and alpha-actin for smooth muscle cell growth [1].
CD34 is a leukocyte antigen that is expressed in various cell types including hematopoietic cells [2].
The cDNA encoding bovine CD34 was cloned, and its nucleotide sequence was determined [2].
Northern blot hybridization with the cDNA as a probe detected CD34 RNA expression in the cerebrum, spleen, heart, and lung of a fetal calf [2].

Biological context of CD34

The identity of the deduced amino acid sequence of the encoded protein to those of human, murine. and canine CD34 proteins was 61.1%, 56.0%, and 66.1%, respectively [2].

Anatomical context of CD34

Monoclonal antibodies against human, murine, and canine CD34 proteins have been used for the identification of lymphohematopoietic stem/progenitor cells [2].
The cultured cells also exhibited positive reaction to CD34 antigen and S-100 antigen, which were negative in smooth muscle cells and fibroblasts [3].

References

In vivo and mechanical properties of peritoneum/fascia as a novel arterial substitute. Sarac, T.P., Carnevale, K., Smedira, N., Tanquilut, E., Augustinos, P., Patel, A., Naska, T., Clair, D., Ouriel, K. J. Vasc. Surg. (2005) [Pubmed]
Cloning of bovine CD34 cDNA. Zhou, J.H., Hikono, H., Ohta, M., Sakurai, M. J. Vet. Med. Sci. (2001) [Pubmed]
Establishment of the culture technique of pulmonary vascular pericytes and its identification in rats. Zhang, Y., Xiong, M., Che, D., Yuan, Y. J. Tongji Med. Univ. (1999) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

CD34	Canis lupus familiaris
CD34	Homo sapiens
LOC713858	Macaca mulatta
Cd34	Mus musculus
CD34	Pan troglodytes
LOC100911324	Rattus norvegicus
Cd34	Rattus norvegicus
LOC779603	Xenopus (Silurana) tropicalis

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