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Gene Review

UCP2  -  uncoupling protein 2 (mitochondrial,...

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High impact information on UCP2


Biological context of UCP2


Anatomical context of UCP2

  • On d 112 of the finishing period, subcutaneous adipose tissue biopsies were obtained from the tailhead of three animals per treatment and analyzed for ACC, SCD, UCP2, and leptin mRNA expression [4].

Other interactions of UCP2


Analytical, diagnostic and therapeutic context of UCP2

  • Using RT-PCR we have successfully cloned a partial UCP2 sequence and a complete UCP3 cDNA [2].


  1. Respiratory uncoupling by UCP1 and UCP2 and superoxide generation in endothelial cell mitochondria. Fink, B.D., Reszka, K.J., Herlein, J.A., Mathahs, M.M., Sivitz, W.I. Am. J. Physiol. Endocrinol. Metab. (2005) [Pubmed]
  2. First evidence of uncoupling protein-2 (UCP-2) and -3 (UCP-3) gene expression in piglet skeletal muscle and adipose tissue. Damon, M., Vincent, A., Lombardi, A., Herpin, P. Gene (2000) [Pubmed]
  3. Octanoate stimulates cytosolic triacylglycerol accumulation and CD36 mRNA expression but inhibits acetyl coenzyme A carboxylase activity in primary cultured bovine mammary epithelial cells. Yonezawa, T., Yonekura, S., Sanosaka, M., Hagino, A., Katoh, K., Obara, Y. J. Dairy Res. (2004) [Pubmed]
  4. Effects of dietary copper on the expression of lipogenic genes and metabolic hormones in steers. Lee, S.H., Engle, T.E., Hossner, K.L. J. Anim. Sci. (2002) [Pubmed]
  5. Bovine UCP2 and UCP3 map to BTA15. Stone, R.T., Rexroad, C.E., Smith, T.P. Anim. Genet. (1999) [Pubmed]
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